Abstract
The glucosinolate‐myrosinase system in plants has been well studied over the years while relatively little research has been undertaken on the bacterial metabolism of glucosinolates. The products of myrosinase based glucosinolate hydrolysis in the human gut are important to health particularly the isothiocyanates as they are shown to have anticancer properties as well as other beneficial roles in human health. This review is concerned with the bacterial metabolism of glucosinolates but is not restricted to the human gut. Isothiocyanate production and nitrile formation are discussed together with the mechanisms of the formation of these compounds. Side chain modification of the methylsulfinylalkyl glucosinolates is reviewed and the implications for bioactivity of the resultant products is also discussed.
Original language | English |
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Article number | 1700991 |
Journal | Molecular Nutrition & Food Research |
Volume | 62 |
Issue number | 18 |
Early online date | 28 May 2018 |
DOIs | |
Publication status | Published - Sept 2018 |
Keywords
- glucosinolates
- gut bacteria
- isothiocyanates
- myrosinase
- nitriles