Hidden variation in polyploid wheat drives local adaptation

Laura-Jayne Gardiner, Ryan Joynson, Jimmy Omony, Rachel Rusholme-Pilcher, Lisa Olohan, Daniel Lang, Caihong Bai, Malcolm Hawkesford, David Salt, Manuel Spannagl, Klaus F.X. Mayer, John Kenny, Michael Bevan, Neil Hall, Anthony Hall

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)
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Abstract

Wheat has been domesticated into a large number of agricultural environments and has the ability to adapt to diverse environments. To understand this process, we survey genotype, repeat content, and DNA methylation across a bread wheat landrace collection representing global genetic diversity. We identify independent variation in methylation, genotype, and transposon copy number. We show that these, so far unexploited, sources of variation have had a significant impact on the wheat genome and that ancestral methylation states become preferentially “hard coded” as single nucleotide polymorphisms (SNPs) via 5-methylcytosine deamination. These mechanisms also drive local adaption, impacting important traits such as heading date and salt tolerance. Methylation and transposon diversity could therefore be used alongside SNP-based markers for breeding.
Original languageEnglish
Pages (from-to)1319-1332
Number of pages14
JournalGenome Research
Volume28
Issue number9
Early online date9 Aug 2018
DOIs
Publication statusPublished - Sep 2018

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