High-intensity exercise attenuates postprandial lipaemia and markers of oxidative stress

Brendan Gabriel, Aivaras Ratkevicius, Patrick Gray, Michael P Frenneaux, Stuart R Gray

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60 Citations (Scopus)


Regular exercise can reduce the risk of CVD (cardiovascular disease). Although moderate-intensity exercise can attenuate postprandial TAG (triacylglycerol), high-intensity intermittent exercise might be a more effective method to improve health. We compared the effects of high-intensity intermittent exercise and 30 min of brisk walking on postprandial TAG, soluble adhesion molecules and markers of oxidative stress. Nine men each completed three 2-day trials. On day 1, subjects rested (control), walked briskly for 30 min (walking) or performed 5×30 s maximal sprints (high-intensity). On day 2, subjects consumed a high-fat meal for breakfast and 3 h later for lunch. Blood samples were taken at various times and analysed for TAG, glucose, insulin, ICAM-1 (intracellular adhesion molecule-1), VCAM-1 (vascular adhesion molecule-1), TBARS (thiobarbituric acid- reactive substances), protein carbonyls and β-hydroxybutyrate. On day 2 of the high-intensity trial, there was a lower (P
Original languageEnglish
Pages (from-to)313-321
Number of pages9
JournalClinical Science
Issue number5
Publication statusPublished - Sep 2012


  • Adult
  • Biological Markers
  • Blood Glucose
  • Dietary Fats
  • Energy Metabolism
  • Exercise
  • Humans
  • Hypertriglyceridemia
  • Insulin
  • Intercellular Adhesion Molecule-1
  • Lipoproteins, VLDL
  • Liver
  • Male
  • Oxidative Stress
  • Postprandial Period
  • Running
  • Triglycerides
  • Vascular Cell Adhesion Molecule-1
  • Walking

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