Household water treatment in developing countries: comparing different intervention types using meta-regression

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Household water treatment (HWT) is being widely promoted as an appropriate intervention for reducing the burden of waterborne disease in poor communities in developing countries. A recent study has raised concerns about the effectiveness of HWT, in part because of concerns over the lack of blinding and in part because of considerable heterogeneity in the reported effectiveness of randomized controlled trials. This study set out to attempt to investigate the causes of this heterogeneity and so identify factors associated with good health gains. Studies identified in an earlier systematic review and meta-analysis were supplemented with more recently published randomized controlled trials. A total of 28 separate studies of randomized controlled trials of HWT with 39 intervention arms were included in the analysis. Heterogeneity was studied using the "metareg" command in Stata. Initial analyses with single candidate predictors were undertaken and all variables significant at the P
Original languageEnglish
Pages (from-to)8991-8997
Number of pages7
JournalEnvironmental Science & Technology
Issue number23
Publication statusPublished - 1 Dec 2009


  • Bias (Epidemiology)
  • Developing Countries
  • Family Characteristics
  • Follow-Up Studies
  • Meta-Analysis as Topic
  • Regression Analysis
  • Risk Factors
  • Water Purification

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