Hydroxy- and alkoxycyclizations of enynes catalyzed by platinum(II) chloride

Antonio M. Echavarren; Maria Munoz-Herranz; María Méndez; Cristina Nevado; Diego J. Cárdenas

doi:10.1055/s-2003-42456

Hydroxy- and alkoxycyclizations of enynes catalyzed by platinum(II) chloride

Antonio M. Echavarren
, Maria Munoz-Herranz
, María Méndez
, Cristina Nevado
, Diego J. Cárdenas

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

The cyclization of 1-en-6-ynes catalyzed by PtCl₂ in the presence of water or alcohols affords five or six-membered ring carbocycles containing hydroxy or alkoxy functional groups in high yields. The alkoxycyclizations can also be performed with AuCl₃ as catalyst. The reaction is stereospecific, atom-economical, and takes place in environmentally friendly solvents.

Original language	English
Pages (from-to)	2898-2902
Number of pages	5
Journal	Synthesis
Issue number	18
DOIs	https://doi.org/10.1055/s-2003-42456
Publication status	Published - 2003

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10.1055/s-2003-42456

Cite this

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title = "Hydroxy- and alkoxycyclizations of enynes catalyzed by platinum(II) chloride",

abstract = "The cyclization of 1-en-6-ynes catalyzed by PtCl2 in the presence of water or alcohols affords five or six-membered ring carbocycles containing hydroxy or alkoxy functional groups in high yields. The alkoxycyclizations can also be performed with AuCl3 as catalyst. The reaction is stereospecific, atom-economical, and takes place in environmentally friendly solvents.",

author = "Echavarren, \{Antonio M.\} and Maria Munoz-Herranz and Mar{\'i}a M{\'e}ndez and Cristina Nevado and C{\'a}rdenas, \{Diego J.\}",

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journal = "Synthesis",

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AU - Echavarren, Antonio M.

AU - Munoz-Herranz, Maria

AU - Méndez, María

AU - Nevado, Cristina

AU - Cárdenas, Diego J.

PY - 2003

Y1 - 2003

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AB - The cyclization of 1-en-6-ynes catalyzed by PtCl2 in the presence of water or alcohols affords five or six-membered ring carbocycles containing hydroxy or alkoxy functional groups in high yields. The alkoxycyclizations can also be performed with AuCl3 as catalyst. The reaction is stereospecific, atom-economical, and takes place in environmentally friendly solvents.

U2 - 10.1055/s-2003-42456

DO - 10.1055/s-2003-42456

M3 - Article

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SP - 2898

EP - 2902

JO - Synthesis

JF - Synthesis

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ER -