Impact of inflammatory markers on platelet inhibition and cardiovascular outcome including stent thrombosis in patients with symptomatic coronary artery disease

Karin Müller, Simon Aichele, Mario Herkommer, Boris Bigalke, Konstantinos Stellos, Patrik Htun, Suzanne Fateh-Moghadam, Andreas E May, Marcus Flather, Meinrad Gawaz, Tobias Geisler

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

There is cumulative evidence that the degree of inflammation correlates with prognosis after percutaneous coronary interventions (PCI). Additionally, there is a cross-link between platelet activation and inflammatory pathways. The aim of the present analysis was to evaluate the association of inflammatory markers and effects of dual antiplatelet therapy on platelet function and outcome in patients undergoing PCI.
Original languageEnglish
Pages (from-to)256-62
Number of pages7
JournalAtherosclerosis
Volume213
Issue number1
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Acute Coronary Syndrome
  • Aged
  • Angioplasty, Balloon
  • Aspirin
  • Blood Platelets
  • C-Reactive Protein
  • Cardiovascular Diseases
  • Coronary Artery Disease
  • Female
  • Humans
  • Inflammation
  • Male
  • Pilot Projects
  • Platelet Activation
  • Stents
  • Ticlopidine
  • Treatment Outcome

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