Importance of tyrosine phosphorylation in receptor kinase complexes

Alberto P. Macho, Rosa Lozano-Durán, Cyril Zipfel

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)
4 Downloads (Pure)


Tyrosine phosphorylation is an important post-translational modification that is known to regulate receptor kinase (RK)-mediated signaling in animals. Plant RKs are annotated as serine/threonine kinases, but recent work has revealed that tyrosine phosphorylation is also crucial for the activation of RK-mediated signaling in plants. These initial observations have paved the way for subsequent detailed studies on the mechanism of activation of plant RKs and the biological relevance of tyrosine phosphorylation for plant growth and immunity. In this Opinion article we review recent reports on the contribution of RK tyrosine phosphorylation in plant growth and immunity; we propose that tyrosine phosphorylation plays a major regulatory role in the initiation and transduction of RK-mediated signaling in plants.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalTrends in Plant Science
Issue number5
Early online date18 Mar 2015
Publication statusPublished - May 2015


  • Phosphorylation
  • Plant Proteins
  • Protein Kinases
  • Protein Processing, Post-Translational
  • Signal Transduction
  • Tyrosine

Cite this