Improved syntheses of n-substituted nitroimidazoles

M. Searcey, P. L. Pye, J. B. Lee

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16 Citations (Scopus)


Nitroimidazoles are of considerable medical and potential agricultural interest as chemotherapeutic agents and potential biocides. The standard route to many 1-substituted nitroimidazoles is the condensation of the conjugate base of the nitroimidazole in a suitable (usually protic) solvent with the appropriate halo compound. Except in a few favourable instances yields are generally low1.
Original languageEnglish
Pages (from-to)1309-1315
Number of pages7
JournalSynthetic Communications
Issue number7-8
Publication statusPublished - 1 Apr 1989

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