In vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermenters

Shazad Mushtaq, Marina Warner, David M Livermore

Research output: Contribution to journalArticlepeer-review

104 Citations (Scopus)

Abstract

NXL104 potentiates ceftazidime and ceftaroline against Enterobacteriaceae with extended-spectrum, AmpC, KPC and OXA β-lactamases. We examined whether similar potentiation was obtained against non-fermenters, which are less permeable than Enterobacteriaceae and have more potent efflux.
Original languageEnglish
Pages (from-to)2376-81
Number of pages6
JournalJournal of Antimicrobial Chemotherapy
Volume65
Issue number11
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Acinetobacter baumannii
  • Anti-Bacterial Agents
  • Azabicyclo Compounds
  • Burkholderia cepacia complex
  • Ceftazidime
  • Drug Synergism
  • Humans
  • Microbial Sensitivity Tests
  • Pseudomonas aeruginosa
  • beta-Lactamases

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