In vitro modeling of central nervous system myelination and remyelination

Andrew A. Jarjour; Hui Zhang; Nina Bauer; Charles ffrench-Constant; Anna Williams

doi:10.1002/glia.21231

In vitro modeling of central nervous system myelination and remyelination

Andrew A. Jarjour, Hui Zhang, Nina Bauer, Charles ffrench-Constant, Anna Williams

Norwich Medical School

Research output: Contribution to journal › Review article › peer-review

55 Citations (Scopus)

Abstract

This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future.

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	Glia
Volume	60
Issue number	1
Early online date	19 Aug 2011
DOIs	https://doi.org/10.1002/glia.21231
Publication status	Published - Jan 2012

Keywords

Culture
Myelin
Oligodendrocyte
Organotypic slice

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10.1002/glia.21231

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In vitro modeling of central nervous system myelination and remyelination

Abstract

Keywords

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