In vitro modeling of central nervous system myelination and remyelination

Andrew A. Jarjour, Hui Zhang, Nina Bauer, Charles ffrench-Constant, Anna Williams

Research output: Contribution to journalReview articlepeer-review

52 Citations (Scopus)

Abstract

This review aims to summarize the current techniques to study myelination and remyelination in culture systems. We attempt to put these into historical context, and to identify the strengths and weaknesses of each approach, which vary depending on the experimental question to be tested. We discuss the difficulty and importance of quantification of myelination and in particular remyelination. Finally, we provide our predictions of how these techniques will and should develop in the future.

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalGlia
Volume60
Issue number1
DOIs
Publication statusPublished - 19 Aug 2011

Keywords

  • Culture
  • Myelin
  • Oligodendrocyte
  • Organotypic slice

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