Four sequential extended-spectrum ß-lactamase—producing isolates of Klebsiella pneumoniae were obtained from a patient after treatment with ertapenem and cultured. The first and fourth isolates were susceptible to ertapenem, whereas the second and third were resistant. All 4 isolates belonged to the same strain and produced a group 1 CTX-M enzyme; additionally, the resistant isolates had lost a porin.
|Journal||Clinical Infectious Diseases|
|Publication status||Published - 1 Jun 2006|