In Vivo Imaging of Bone Marrow Long-Chain Fatty Acid Uptake

Jayna J. Mistry, Stuart A. Rushworth

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In vivo imaging enables the detection and visualization of many different processes occurring within the body. Fatty acid uptake is a fundamental cellular process which is essential for the use of free fatty acids (FFAs) as a fuel source for metabolism. Detection and visualization of in vivo FFA uptake in the bone marrow has been relatively unknown. Here, we describe the process of non-invasive bioluminescent imaging of in vivo FFA uptake within the bone marrow.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc
Pages43-49
Number of pages7
ISBN (Electronic)978-1-0716-3247-5
ISBN (Print)978-1-0716-3246-8
DOIs
Publication statusPublished - 2023

Publication series

NameMethods in Molecular Biology
Volume2675
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Bone marrow
  • Free fatty acids
  • Hematopoietic cells
  • In vivo imaging
  • β-Oxidation

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