Increased atrial contribution to left ventricular filling compensates for impaired early filling during exercise in heart failure with preserved ejection fraction

Thanh T Phan, Khalid Abozguia, Ganesh Nallur Shivu, Ibrar Ahmed, Francisco Leyva, Kiran Patel, Michael Frenneaux

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40 Citations (Scopus)


The role of left atrial (LA) function on exercise remains poorly understood in heart failure with preserved ejection fraction (HfpEF) despite its key role in optimizing left ventricular (LV) diastolic function. We used resting and exercise radionuclide ventriculography to investigate the role of LA function in the pathophysiology of HfpEF.
Original languageEnglish
Pages (from-to)890-7
Number of pages8
JournalJournal of Cardiac Failure
Issue number10
Publication statusPublished - Dec 2009


  • Aged
  • Atrial Function, Left
  • Exercise
  • Exercise Test
  • Female
  • Heart Failure
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Stroke Volume
  • Ventricular Dysfunction, Left

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