Abstract
In our cohort considered at high risk (HR) of developing schizophrenia, we previously found a significant difference in extent of right prefrontal cortical folding between those who subsequently developed schizophrenia and a matched group who remained well. This study aimed to determine if this preexisting difference distinguished 17 individuals who developed schizophrenia from the 128 HR individuals in the cohort who remained well and to explore possible underlying differences in cortical composition.
Original language | English |
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Pages (from-to) | 722-9 |
Number of pages | 8 |
Journal | Biological Psychiatry |
Volume | 62 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Oct 2007 |
Keywords
- Adolescent
- Adult
- Cohort Studies
- Female
- Functional Laterality
- Humans
- Image Processing, Computer-Assisted
- Logistic Models
- Longitudinal Studies
- Magnetic Resonance Imaging
- Male
- Neuropsychological Tests
- Prefrontal Cortex
- Prospective Studies
- Psychiatric Status Rating Scales
- Risk
- Schizophrenia