Influence of the APOC3 −2854T>G polymorphism on plasma lipid levels: effect of age and gender

Anne Marie Minihane, Yvonne E. Finnegan, Philippa Talmud, Elizabeth C. Leigh-Firbank, Christine M. Williams

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The APOC3 −2854T>G polymorphism lies in the APOC3–A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype–triglyceride interactions.
Original languageEnglish
Pages (from-to)311-314
Number of pages4
JournalBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Issue number3
Publication statusPublished - 8 Aug 2002

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