The APOC3 −2854T>G polymorphism lies in the APOC3–A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype–triglyceride interactions.
|Number of pages||4|
|Journal||Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids|
|Publication status||Published - 8 Aug 2002|