Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

Sameer Jhavar; Daniel Brewer; Sandra Edwards; Zsofia Kote-Jarai; Gerhardt Attard; Jeremy Clark; Penny Flohr; Timothy Christmas; Alan Thompson; Matthew Parker; Christopher Shepherd; Ulf-Hakan Stenman; Tania Marchbank; Raymond J Playford; Christopher Woodhouse; Christopher Ogden; Cyril Fisher; Gyula Kovacs; Cathy Corbishley; Charles Jameson; Andy Norman; Johann De-Bono; Anders Bjartell; Rosalind Eeles; Colin S Cooper

doi:10.1111/j.1464-410X.2008.08200.x

Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

Sameer Jhavar, Daniel Brewer, Sandra Edwards, Zsofia Kote-Jarai, Gerhardt Attard, Jeremy Clark, Penny Flohr, Timothy Christmas, Alan Thompson, Matthew Parker, Christopher Shepherd, Ulf-Hakan Stenman, Tania Marchbank, Raymond J Playford, Christopher Woodhouse, Christopher Ogden, Cyril Fisher, Gyula Kovacs, Cathy Corbishley, Charles JamesonAndy Norman, Johann De-Bono, Anders Bjartell, Rosalind Eeles, Colin S Cooper

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

To integrate the mapping of ERG alterations with the collection of expression microarray (EMA) data, as previous EMA analyses have failed to consider the genetic heterogeneity and complex patterns of ERG alteration frequently found in cancerous prostates.

Original language	English
Pages (from-to)	1256-69
Number of pages	14
Journal	BJU International
Volume	103
Issue number	9
DOIs	https://doi.org/10.1111/j.1464-410X.2008.08200.x
Publication status	Published - May 2009

Keywords

Carrier Proteins
Chromosome Mapping
Gene Expression Profiling
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Male
Prostatic Neoplasms
Trans-Activators

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1464-410X.2008.08200.x

Cite this

Jhavar, S., Brewer, D., Edwards, S., Kote-Jarai, Z., Attard, G., Clark, J., Flohr, P., Christmas, T., Thompson, A., Parker, M., Shepherd, C., Stenman, U-H., Marchbank, T., Playford, R. J., Woodhouse, C., Ogden, C., Fisher, C., Kovacs, G., Corbishley, C., ... Cooper, C. S. (2009). Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer. BJU International, 103(9), 1256-69. https://doi.org/10.1111/j.1464-410X.2008.08200.x

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title = "Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer",

abstract = "To integrate the mapping of ERG alterations with the collection of expression microarray (EMA) data, as previous EMA analyses have failed to consider the genetic heterogeneity and complex patterns of ERG alteration frequently found in cancerous prostates.",

keywords = "Carrier Proteins, Chromosome Mapping, Gene Expression Profiling, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Male, Prostatic Neoplasms, Trans-Activators",

author = "Sameer Jhavar and Daniel Brewer and Sandra Edwards and Zsofia Kote-Jarai and Gerhardt Attard and Jeremy Clark and Penny Flohr and Timothy Christmas and Alan Thompson and Matthew Parker and Christopher Shepherd and Ulf-Hakan Stenman and Tania Marchbank and Playford, {Raymond J} and Christopher Woodhouse and Christopher Ogden and Cyril Fisher and Gyula Kovacs and Cathy Corbishley and Charles Jameson and Andy Norman and Johann De-Bono and Anders Bjartell and Rosalind Eeles and Cooper, {Colin S}",

year = "2009",

month = may,

doi = "10.1111/j.1464-410X.2008.08200.x",

language = "English",

volume = "103",

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Jhavar, S, Brewer, D, Edwards, S, Kote-Jarai, Z, Attard, G, Clark, J, Flohr, P, Christmas, T, Thompson, A, Parker, M, Shepherd, C, Stenman, U-H, Marchbank, T, Playford, RJ, Woodhouse, C, Ogden, C, Fisher, C, Kovacs, G, Corbishley, C, Jameson, C, Norman, A, De-Bono, J, Bjartell, A, Eeles, R & Cooper, CS 2009, 'Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer', BJU International, vol. 103, no. 9, pp. 1256-69. https://doi.org/10.1111/j.1464-410X.2008.08200.x

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T1 - Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

AU - Jhavar, Sameer

AU - Brewer, Daniel

AU - Edwards, Sandra

AU - Kote-Jarai, Zsofia

AU - Attard, Gerhardt

AU - Clark, Jeremy

AU - Flohr, Penny

AU - Christmas, Timothy

AU - Thompson, Alan

AU - Parker, Matthew

AU - Shepherd, Christopher

AU - Stenman, Ulf-Hakan

AU - Marchbank, Tania

AU - Playford, Raymond J

AU - Woodhouse, Christopher

AU - Ogden, Christopher

AU - Fisher, Cyril

AU - Kovacs, Gyula

AU - Corbishley, Cathy

AU - Jameson, Charles

AU - Norman, Andy

AU - De-Bono, Johann

AU - Bjartell, Anders

AU - Eeles, Rosalind

AU - Cooper, Colin S

PY - 2009/5

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AB - To integrate the mapping of ERG alterations with the collection of expression microarray (EMA) data, as previous EMA analyses have failed to consider the genetic heterogeneity and complex patterns of ERG alteration frequently found in cancerous prostates.

KW - Carrier Proteins

KW - Chromosome Mapping

KW - Gene Expression Profiling

KW - Humans

KW - Immunohistochemistry

KW - In Situ Hybridization, Fluorescence

KW - Male

KW - Prostatic Neoplasms

KW - Trans-Activators

U2 - 10.1111/j.1464-410X.2008.08200.x

DO - 10.1111/j.1464-410X.2008.08200.x

M3 - Article

C2 - 19040532

VL - 103

SP - 1256

EP - 1269

JO - BJU International

JF - BJU International

SN - 1464-4096

IS - 9

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