Abstract
SSc is a connective tissue, multisystem disorder of unknown aetiology. The gastrointestinal tract (GIT) is affected in up to 90% of patients. The exact pathophysiology of GIT involvement is not known, but it is related to both neurogenic and myogenic abnormalities as well as possible vascular and ischaemic changes. Thinning of the internal anal sphincter (IAS) has been demonstrated in SSc with faecal incontinence. We aimed to investigate anal sphincter structure in patients with SSc.
| Original language | English |
|---|---|
| Pages (from-to) | 1596-602 |
| Number of pages | 7 |
| Journal | Rheumatology |
| Volume | 50 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 2011 |
Keywords
- Adult
- Aged
- Anal Canal
- Case-Control Studies
- Endosonography
- Fecal Incontinence
- Female
- Humans
- Intestinal Diseases
- Male
- Manometry
- Middle Aged
- Questionnaires
- Scleroderma, Systemic