International Collaborative Ovarian Neoplasm trial 1: A randomized trial of adjuvant chemotherapy in women with early-stage ovarian cancer

International Collaborative Ovarian Neoplasm (ICON) collaborators

doi:10.1093/jnci/95.2.125

International Collaborative Ovarian Neoplasm trial 1: A randomized trial of adjuvant chemotherapy in women with early-stage ovarian cancer

International Collaborative Ovarian Neoplasm (ICON) collaborators

Research output: Contribution to journal › Article › peer-review

260 Citations (Scopus)

Abstract

The question of whether platinum-based adjuvant chemotherapy can improve outcomes in patients with early-stage epithelial ovarian cancer is an important one. We carried out a multicenter, open randomized trial to determine whether adjuvant chemotherapy would improve overall survival and prolong recurrence-free survival in women with early-stage epithelial ovarian cancer.

Original language	English
Pages (from-to)	125-132
Number of pages	8
Journal	Journal of the National Cancer Institute
Volume	95
Issue number	2
DOIs	https://doi.org/10.1093/jnci/95.2.125
Publication status	Published - 15 Jan 2003

Keywords

Aged
Aged, 80 and over
Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Carboplatin
Carcinoma
Chemotherapy, Adjuvant
Cisplatin
Confidence Intervals
Disease-Free Survival
Drug Administration Schedule
Female
Humans
International Cooperation
Middle Aged
Neoplasm Staging
Observation
Odds Ratio
Ovarian Neoplasms
Survival Analysis
Treatment Outcome

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/jnci/95.2.125

Cite this

@article{ff3a55382f834ffda0caa622389aeb8d,

title = "International Collaborative Ovarian Neoplasm trial 1: A randomized trial of adjuvant chemotherapy in women with early-stage ovarian cancer",

abstract = "The question of whether platinum-based adjuvant chemotherapy can improve outcomes in patients with early-stage epithelial ovarian cancer is an important one. We carried out a multicenter, open randomized trial to determine whether adjuvant chemotherapy would improve overall survival and prolong recurrence-free survival in women with early-stage epithelial ovarian cancer.",

keywords = "Aged, Aged, 80 and over, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Carcinoma, Chemotherapy, Adjuvant, Cisplatin, Confidence Intervals, Disease-Free Survival, Drug Administration Schedule, Female, Humans, International Cooperation, Middle Aged, Neoplasm Staging, Observation, Odds Ratio, Ovarian Neoplasms, Survival Analysis, Treatment Outcome",

author = "Nicoletta Colombo and David Guthrie and Stefania Chiari and Mahesh Parmar and Wendi Qian and Swart, {Ann Marie} and Valter Torri and Christopher Williams and Andrea Lissoni and Cristina Bonazzi and {International Collaborative Ovarian Neoplasm (ICON) collaborators}",

year = "2003",

month = jan,

day = "15",

doi = "10.1093/jnci/95.2.125",

language = "English",

volume = "95",

pages = "125--132",

journal = "Journal of the National Cancer Institute",

issn = "0027-8874",

publisher = "Oxford University Press",

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TY - JOUR

T1 - International Collaborative Ovarian Neoplasm trial 1: A randomized trial of adjuvant chemotherapy in women with early-stage ovarian cancer

AU - Colombo, Nicoletta

AU - Guthrie, David

AU - Chiari, Stefania

AU - Parmar, Mahesh

AU - Qian, Wendi

AU - Swart, Ann Marie

AU - Torri, Valter

AU - Williams, Christopher

AU - Lissoni, Andrea

AU - Bonazzi, Cristina

AU - International Collaborative Ovarian Neoplasm (ICON) collaborators

PY - 2003/1/15

Y1 - 2003/1/15

N2 - The question of whether platinum-based adjuvant chemotherapy can improve outcomes in patients with early-stage epithelial ovarian cancer is an important one. We carried out a multicenter, open randomized trial to determine whether adjuvant chemotherapy would improve overall survival and prolong recurrence-free survival in women with early-stage epithelial ovarian cancer.

AB - The question of whether platinum-based adjuvant chemotherapy can improve outcomes in patients with early-stage epithelial ovarian cancer is an important one. We carried out a multicenter, open randomized trial to determine whether adjuvant chemotherapy would improve overall survival and prolong recurrence-free survival in women with early-stage epithelial ovarian cancer.

KW - Aged

KW - Aged, 80 and over

KW - Antineoplastic Agents

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Carboplatin

KW - Carcinoma

KW - Chemotherapy, Adjuvant

KW - Cisplatin

KW - Confidence Intervals

KW - Disease-Free Survival

KW - Drug Administration Schedule

KW - Female

KW - Humans

KW - International Cooperation

KW - Middle Aged

KW - Neoplasm Staging

KW - Observation

KW - Odds Ratio

KW - Ovarian Neoplasms

KW - Survival Analysis

KW - Treatment Outcome

U2 - 10.1093/jnci/95.2.125

DO - 10.1093/jnci/95.2.125

M3 - Article

C2 - 12529345

VL - 95

SP - 125

EP - 132

JO - Journal of the National Cancer Institute

JF - Journal of the National Cancer Institute

SN - 0027-8874

IS - 2

ER -