International Consensus Statement on Rhinology and Allergy: Rhinosinusitis

Richard Orlandi, Todd T. Kingdom, Timothy L. Smith, Benjamin Bleier, Adam DeConde, Amber Luong, David M. Poetker, Zachary Soler, Kevin C. Welch, Sarah K. Wise, Nithin Adappa, Jeremiah A. Alt, Wilma Terezinha Anselmo-Lima, Claus Bachert, Fuad M. Baroody, Pete S. Batra, Manuel Bernal-Sprekelsen, Daniel Beswick, Neil Bhattacharyya, Rakesh K. ChandraEugene Chang, Alexander Chiu, Naweed Chowdhury, Martin J. Citardi, Noam Cohen, David B. Conley, John DelGaudio, Martin Desrosiers, Richard Douglas, Jean Anderson Eloy, Wytske J. Fokkens, Stacey T. Gray, David A. Gudis, Daniel L. Hamilos, Joseph K. Han, Richard Harvey, Peter Hellings, Eric H. Holbrook, Claire Hopkins, Peter Hwang, Amin R. Javer, Rong-San Jiang, David Kennedy, Robert Kern, Tanya Laidlaw, Devyani Lal, Andrew Lane, Heung-Man Lee, Jivianne T. Lee, Joshua M. Levy, Sandra Y. Lin, Valerie Lund, Kevin C. McMains, Ralph Metson, Joaquim Mullol, Robert Naclerio, Gretchen Oakley, Nobuyoshi Otori, James N. Palmer, Sanjay R. Parikh, Desiderio Passali, Zara Patel, Anju Peters, Carl Philpott, Alkis J. Psaltis, Vijay R. Ramakrishnan, Murugappan Ramanathan, Hwan-Jung Roh, Luke Rudmik, Raymond Sacks, Rodney J. Schlosser, Ahmad Sedaghat, Brent Senior, Raj Sindwani, Kristine Smith, Kornkiat Snidvongs, Michael Stewart, Jeffrey Suh, Bruce K. Tan, Justin H. Turner, Cornelis M. van Drunen, Richard Voegels, De-Yun Wang, Bradford A. Woodworth, Peter-John Wormald, Erin D. Wright, Carol Yan, Luo Zhang, Bing Zhou

Research output: Contribution to journalReview articlepeer-review

31 Citations (Scopus)


Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document.

Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary.

Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided.

Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS.
Original languageEnglish
Pages (from-to)213-739
Number of pages527
JournalInternational Forum of Allergy & Rhinology
Issue number3
Early online date24 Nov 2020
Publication statusPublished - Mar 2021


  • acute rhinosinusitis
  • chronic rhinosinusitis
  • endoscopic sinus surgery
  • evidence-based medicine
  • recurrent acute rhinosinusitis
  • rhinosinusitis
  • systematic review

Cite this