International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin

Simon Le Hello; Rene S. Hendriksen; Benoît Doublet; Ian Fisher; Eva Møller Nielsen; Jean M. Whichard; Brahim Bouchrif; Kayode Fashae; Sophie A. Granier; Nathalie Jourdan-Da Silva; Axel Cloeckaert; E. John Threlfall; Frederick J. Angulo; Frank M. Aarestrup; John Wain; François-Xavier Weill

doi:10.1093/infdis/jir409

International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin

Simon Le Hello, Rene S. Hendriksen, Benoît Doublet, Ian Fisher, Eva Møller Nielsen, Jean M. Whichard, Brahim Bouchrif, Kayode Fashae, Sophie A. Granier, Nathalie Jourdan-Da Silva, Axel Cloeckaert, E. John Threlfall, Frederick J. Angulo, Frank M. Aarestrup, John Wain, François-Xavier Weill

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

216 Citations (Scopus)

Abstract

National Salmonella surveillance systems from France, England and Wales, Denmark, and the United States identified the recent emergence of multidrug-resistant isolates of Salmonella enterica serotype Kentucky displaying high-level resistance to ciprofloxacin. A total of 489 human cases were identified during the period from 2002 (3 cases) to 2008 (174 cases). These isolates belonged to a single clone defined by the multilocus sequence type ST198, the XbaI-pulsed-field gel electrophoresis cluster X1, and the presence of the Salmonella genomic island 1 variant SGI1-K. This clone was probably selected in 3 steps in Egypt during the 1990s and the early 2000s and has now spread to several countries in Africa and, more recently, in the Middle East. Poultry has been identified as a potential major vehicle for infection by this clone. Continued surveillance and appropriate control measures should be implemented by national and international authorities to limit the spread of this strain.

Original language	English
Pages (from-to)	675-684
Number of pages	10
Journal	Journal of Infectious Diseases
Volume	204
Issue number	5
DOIs	https://doi.org/10.1093/infdis/jir409
Publication status	Published - 1 Sep 2011

Access to Document

10.1093/infdis/jir409

Cite this

Le Hello, S., Hendriksen, R. S., Doublet, B., Fisher, I., Møller Nielsen, E., Whichard, J. M., Bouchrif, B., Fashae, K., Granier, S. A., Jourdan-Da Silva, N., Cloeckaert, A., Threlfall, E. J., Angulo, F. J., Aarestrup, F. M., Wain, J., & Weill, F-X. (2011). International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin. Journal of Infectious Diseases, 204(5), 675-684. https://doi.org/10.1093/infdis/jir409

@article{8816c6c6f15e45d89c51fe40249920d7,

title = "International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin",

abstract = "National Salmonella surveillance systems from France, England and Wales, Denmark, and the United States identified the recent emergence of multidrug-resistant isolates of Salmonella enterica serotype Kentucky displaying high-level resistance to ciprofloxacin. A total of 489 human cases were identified during the period from 2002 (3 cases) to 2008 (174 cases). These isolates belonged to a single clone defined by the multilocus sequence type ST198, the XbaI-pulsed-field gel electrophoresis cluster X1, and the presence of the Salmonella genomic island 1 variant SGI1-K. This clone was probably selected in 3 steps in Egypt during the 1990s and the early 2000s and has now spread to several countries in Africa and, more recently, in the Middle East. Poultry has been identified as a potential major vehicle for infection by this clone. Continued surveillance and appropriate control measures should be implemented by national and international authorities to limit the spread of this strain.",

author = "{Le Hello}, Simon and Hendriksen, {Rene S.} and Beno{\^i}t Doublet and Ian Fisher and {M{\o}ller Nielsen}, Eva and Whichard, {Jean M.} and Brahim Bouchrif and Kayode Fashae and Granier, {Sophie A.} and {Jourdan-Da Silva}, Nathalie and Axel Cloeckaert and Threlfall, {E. John} and Angulo, {Frederick J.} and Aarestrup, {Frank M.} and John Wain and Fran{\c c}ois-Xavier Weill",

year = "2011",

month = sep,

day = "1",

doi = "10.1093/infdis/jir409",

language = "English",

volume = "204",

pages = "675--684",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

number = "5",

}

Le Hello, S, Hendriksen, RS, Doublet, B, Fisher, I, Møller Nielsen, E, Whichard, JM, Bouchrif, B, Fashae, K, Granier, SA, Jourdan-Da Silva, N, Cloeckaert, A, Threlfall, EJ, Angulo, FJ, Aarestrup, FM, Wain, J & Weill, F-X 2011, 'International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin', Journal of Infectious Diseases, vol. 204, no. 5, pp. 675-684. https://doi.org/10.1093/infdis/jir409

TY - JOUR

T1 - International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin

AU - Le Hello, Simon

AU - Hendriksen, Rene S.

AU - Doublet, Benoît

AU - Fisher, Ian

AU - Møller Nielsen, Eva

AU - Whichard, Jean M.

AU - Bouchrif, Brahim

AU - Fashae, Kayode

AU - Granier, Sophie A.

AU - Jourdan-Da Silva, Nathalie

AU - Cloeckaert, Axel

AU - Threlfall, E. John

AU - Angulo, Frederick J.

AU - Aarestrup, Frank M.

AU - Wain, John

AU - Weill, François-Xavier

PY - 2011/9/1

Y1 - 2011/9/1

N2 - National Salmonella surveillance systems from France, England and Wales, Denmark, and the United States identified the recent emergence of multidrug-resistant isolates of Salmonella enterica serotype Kentucky displaying high-level resistance to ciprofloxacin. A total of 489 human cases were identified during the period from 2002 (3 cases) to 2008 (174 cases). These isolates belonged to a single clone defined by the multilocus sequence type ST198, the XbaI-pulsed-field gel electrophoresis cluster X1, and the presence of the Salmonella genomic island 1 variant SGI1-K. This clone was probably selected in 3 steps in Egypt during the 1990s and the early 2000s and has now spread to several countries in Africa and, more recently, in the Middle East. Poultry has been identified as a potential major vehicle for infection by this clone. Continued surveillance and appropriate control measures should be implemented by national and international authorities to limit the spread of this strain.

AB - National Salmonella surveillance systems from France, England and Wales, Denmark, and the United States identified the recent emergence of multidrug-resistant isolates of Salmonella enterica serotype Kentucky displaying high-level resistance to ciprofloxacin. A total of 489 human cases were identified during the period from 2002 (3 cases) to 2008 (174 cases). These isolates belonged to a single clone defined by the multilocus sequence type ST198, the XbaI-pulsed-field gel electrophoresis cluster X1, and the presence of the Salmonella genomic island 1 variant SGI1-K. This clone was probably selected in 3 steps in Egypt during the 1990s and the early 2000s and has now spread to several countries in Africa and, more recently, in the Middle East. Poultry has been identified as a potential major vehicle for infection by this clone. Continued surveillance and appropriate control measures should be implemented by national and international authorities to limit the spread of this strain.

U2 - 10.1093/infdis/jir409

DO - 10.1093/infdis/jir409

M3 - Article

VL - 204

SP - 675

EP - 684

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 5

ER -