Investigation of a unified strategy for the synthesis of anatoxin analogues: Scope and limitations

Stephen J. Roe, David L. Hughes, Pooja Aggarwal, Robert A. Stockman

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Syntheses of the potent neurotoxins and biochemical probes anatoxin-a and homoanatoxin and several analogues by a combined two-directional synthesis-tandem reaction strategy are presented. Key steps include an oxidative desymmetrisation and a tandem Michael-intramolecular Mannich cyclisation.
Original languageEnglish
Pages (from-to)3775-3784
Issue number22
Publication statusPublished - 1 Nov 2009

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