Isolation of multiple carbapenemase-producing Gram-negative bacilli from a patient recently hospitalized in Nigeria

Andrew Walkty, Matthew Gilmour, Patricia Simner, John M Embil, David Boyd, Michael Mulvey, James Karlowsky

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A 29-year-old female transferred to a tertiary care hospital in Winnipeg, Canada, after a prolonged period of hospitalization in Nigeria was found to be colonized with a VIM-2-producing Pseudomonas aeruginosa, a NDM-1-producing Klebsiella pneumoniae, and an OXA-181-producing Escherichia coli. Detection of carbapenemase-producing organisms from a rectal swab was accomplished by screening with chromogenic media, followed by confirmation with the Rapid CARB Screen kit (Rosco Diagnostica, Taastrup, Denmark). This case illustrates the need for clinical microbiology laboratories to have a protocol in place to screen patients for carbapenemase producers, even in countries where these organisms are rarely encountered.

Original languageEnglish
Pages (from-to)296-298
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume81
Issue number4
Early online date19 Jan 2015
DOIs
Publication statusPublished - Apr 2015

Keywords

  • Adult
  • Bacterial Proteins/genetics
  • Bacteriological Techniques
  • Canada
  • Carrier State/microbiology
  • Escherichia coli/enzymology
  • Female
  • Gram-Negative Bacterial Infections/microbiology
  • Hospitalization
  • Humans
  • Klebsiella pneumoniae/enzymology
  • Nigeria
  • Pseudomonas aeruginosa/enzymology
  • beta-Lactamases/genetics

Cite this