Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis

Gang Zhao, Maximilian Hatting, Yulia A Nevzorova, Jin Peng, Wei Hu, Mark V Boekschoten, Tania Roskams, Michael Muller, Nikolaus Gassler, Christian Liedtke, Roger J Davis, Francisco Javier Cubero, Christian Trautwein

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)

Abstract

The c-Jun N-terminal kinase-1 (Jnk1) gene has been shown to be involved in liver fibrosis. Here, we aimed to investigate the molecular mechanism and define the cell type involved in mediating the Jnk1-dependent effect on liver fibrogenesis.
Original languageEnglish
Pages (from-to)1159-72
Number of pages13
JournalGut
Volume63
Issue number7
Early online date13 Sep 2013
DOIs
Publication statusPublished - Jul 2014

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