Abstract
Quenching the anion generated from a 2(ω-carboranylalkyl)dithiane with HO at -78°C and at 0°C intoduced deuterium exclusively at C-2 of the carborane. Extension of this model reaction to a bioreductively-targetted carborane allowed the synthesis of 2-[H]- and 2-[H]-isotopomers of a nitroimidazole-carborane which is of interest in boron neutron capture therapy (BNCT) of cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 881-885 |
| Number of pages | 5 |
| Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
| Volume | 34 |
| Issue number | 9 |
| Publication status | Published - 1 Jan 1994 |
