Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function

Samantha Kew; Tapati Banerjee; Anne-Marie Minihane; Yvonne E. Finnegan; Reto Muggli; Ruud Albers; Christine M. Williams; Philip C. Calder

doi:10.1093/ajcn/77.5.1287

Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function

Samantha Kew
, Tapati Banerjee
, Anne-Marie Minihane
, Yvonne E. Finnegan
, Reto Muggli
, Ruud Albers
, Christine M. Williams
, Philip C. Calder

Research output: Contribution to journal › Article › peer-review

148 Citations (Scopus)

Abstract

Greatly increasing dietary flaxseed oil [rich in the n-3 polyunsaturated fatty acid (PUFA) alpha-linolenic acid (ALA)] or fish oil [rich in the long-chain n-3 PUFAs eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids] can reduce markers of immune cell function. The effects of more modest doses are unclear, and it is not known whether ALA has the same effects as its long-chain derivatives.

Original language	English
Pages (from-to)	1287-1295
Number of pages	9
Journal	American Journal of Clinical Nutrition
Volume	77
Issue number	5
DOIs	https://doi.org/10.1093/ajcn/77.5.1287
Publication status	Published - May 2003

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

Keywords

Adult
Aged
Cytokines
Docosahexaenoic Acids
Double-Blind Method
Eicosapentaenoic Acid
Female
Fish Oils
Humans
Hypersensitivity, Delayed
Leukocytes, Mononuclear
Linseed Oil
Lymphocyte Activation
Male
Middle Aged
Neutrophils
Phagocytosis
Phospholipids
Respiratory Burst
alpha-Linolenic Acid

Access to Document

10.1093/ajcn/77.5.1287

Cite this

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title = "Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function",

abstract = "Greatly increasing dietary flaxseed oil [rich in the n-3 polyunsaturated fatty acid (PUFA) alpha-linolenic acid (ALA)] or fish oil [rich in the long-chain n-3 PUFAs eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids] can reduce markers of immune cell function. The effects of more modest doses are unclear, and it is not known whether ALA has the same effects as its long-chain derivatives.",

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author = "Samantha Kew and Tapati Banerjee and Anne-Marie Minihane and Finnegan, \{Yvonne E.\} and Reto Muggli and Ruud Albers and Williams, \{Christine M.\} and Calder, \{Philip C.\}",

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T1 - Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function

AU - Kew, Samantha

AU - Banerjee, Tapati

AU - Minihane, Anne-Marie

AU - Finnegan, Yvonne E.

AU - Muggli, Reto

AU - Albers, Ruud

AU - Williams, Christine M.

AU - Calder, Philip C.

PY - 2003/5

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AB - Greatly increasing dietary flaxseed oil [rich in the n-3 polyunsaturated fatty acid (PUFA) alpha-linolenic acid (ALA)] or fish oil [rich in the long-chain n-3 PUFAs eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids] can reduce markers of immune cell function. The effects of more modest doses are unclear, and it is not known whether ALA has the same effects as its long-chain derivatives.

KW - Adult

KW - Aged

KW - Cytokines

KW - Docosahexaenoic Acids

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KW - Eicosapentaenoic Acid

KW - Female

KW - Fish Oils

KW - Humans

KW - Hypersensitivity, Delayed

KW - Leukocytes, Mononuclear

KW - Linseed Oil

KW - Lymphocyte Activation

KW - Male

KW - Middle Aged

KW - Neutrophils

KW - Phagocytosis

KW - Phospholipids

KW - Respiratory Burst

KW - alpha-Linolenic Acid

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