Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment

V van der Velpen; P C Hollman; M van Nielen; E G Schouten; M Mensink; P Van't Veer; A Geelen

doi:10.1038/ejcn.2014.108

Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment

V van der Velpen, P C Hollman, M van Nielen, E G Schouten, M Mensink, P Van't Veer, A Geelen

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

Isoflavones are present in soy foods and soy-based supplements. Despite low plasma isoflavone concentrations in the general Western population, concentrations in supplement users exceed those suggested to be beneficial for health in Asian populations, raising concerns for adverse effects. To aid risk assessment, quantification of the relation between isoflavone intake and plasma concentrations is essential.

Original language	English
Pages (from-to)	1141-7
Number of pages	7
Journal	European Journal of Clinical Nutrition
Volume	68
Issue number	10
DOIs	https://doi.org/10.1038/ejcn.2014.108
Publication status	Published - Oct 2014

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10.1038/ejcn.2014.108

Cite this

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title = "Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment",

abstract = "Isoflavones are present in soy foods and soy-based supplements. Despite low plasma isoflavone concentrations in the general Western population, concentrations in supplement users exceed those suggested to be beneficial for health in Asian populations, raising concerns for adverse effects. To aid risk assessment, quantification of the relation between isoflavone intake and plasma concentrations is essential.",

author = "{van der Velpen}, V and Hollman, {P C} and {van Nielen}, M and Schouten, {E G} and M Mensink and {Van't Veer}, P and A Geelen",

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AU - Mensink, M

AU - Van't Veer, P

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AB - Isoflavones are present in soy foods and soy-based supplements. Despite low plasma isoflavone concentrations in the general Western population, concentrations in supplement users exceed those suggested to be beneficial for health in Asian populations, raising concerns for adverse effects. To aid risk assessment, quantification of the relation between isoflavone intake and plasma concentrations is essential.

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