Large-scale population-based study shows no evidence of association between common polymorphism of the VDR gene and BMD in British women

Helen M Macdonald; Fiona E McGuigan; Alison Stewart; Alison J Black; WD Fraser; Stuart Ralston; David M Reid

doi:10.1359/JBMR.050906

Large-scale population-based study shows no evidence of association between common polymorphism of the VDR gene and BMD in British women

Helen M Macdonald, Fiona E McGuigan, Alison Stewart, Alison J Black, WD Fraser, Stuart Ralston, David M Reid

Research output: Contribution to journal › Article

83 Citations (Scopus)

Abstract

The VDR is a candidate gene for osteoporosis. Here we studied five common polymorphisms of VDR in relation to calcium intake and vitamin D status in a population-based cohort of 3100 British women, but found no significant association with bone mass, bone loss, or fracture.

Original language	English
Pages (from-to)	151-162
Number of pages	12
Journal	Journal of Bone and Mineral Research
Volume	21
Issue number	1
DOIs	https://doi.org/10.1359/JBMR.050906
Publication status	Published - Jan 2006

Access to Document

10.1359/JBMR.050906

Cite this

@article{105b9f1b783d4ce1b7a6297027a02b04,

title = "Large-scale population-based study shows no evidence of association between common polymorphism of the VDR gene and BMD in British women",

abstract = "The VDR is a candidate gene for osteoporosis. Here we studied five common polymorphisms of VDR in relation to calcium intake and vitamin D status in a population-based cohort of 3100 British women, but found no significant association with bone mass, bone loss, or fracture.",

author = "Macdonald, {Helen M} and McGuigan, {Fiona E} and Alison Stewart and Black, {Alison J} and WD Fraser and Stuart Ralston and Reid, {David M}",

year = "2006",

month = jan,

doi = "10.1359/JBMR.050906",

language = "English",

volume = "21",

pages = "151--162",

journal = "Journal of Bone and Mineral Research",

issn = "1523-4681",

publisher = "Wiley",

number = "1",

}

TY - JOUR

T1 - Large-scale population-based study shows no evidence of association between common polymorphism of the VDR gene and BMD in British women

AU - Macdonald, Helen M

AU - McGuigan, Fiona E

AU - Stewart, Alison

AU - Black, Alison J

AU - Fraser, WD

AU - Ralston, Stuart

AU - Reid, David M

PY - 2006/1

Y1 - 2006/1

N2 - The VDR is a candidate gene for osteoporosis. Here we studied five common polymorphisms of VDR in relation to calcium intake and vitamin D status in a population-based cohort of 3100 British women, but found no significant association with bone mass, bone loss, or fracture.

AB - The VDR is a candidate gene for osteoporosis. Here we studied five common polymorphisms of VDR in relation to calcium intake and vitamin D status in a population-based cohort of 3100 British women, but found no significant association with bone mass, bone loss, or fracture.

U2 - 10.1359/JBMR.050906

DO - 10.1359/JBMR.050906

M3 - Article

SN - 1523-4681

VL - 21

SP - 151

EP - 162

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

IS - 1

ER -