Late-onset sepsis in a preterm twin may harbinger life-threatening sepsis for the asymptomatic co-twin

Jayaram R. Pai, Catherine H. Tremlett, Paul Clarke

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7 Citations (Scopus)


We report extremely preterm twins who developed late-onset Escherichia coli sepsis in the second postnatal week within a short time of each other. The asymptomatic twin was not treated initially, and within 2 days developed life-threatening septicemia and meningitis, followed by other serious morbidity. Occurrence of late-onset sepsis in a twin should prompt concurrent investigation and consideration of presumptive treatment of the apparently asymptomatic co-twin.

Original languageEnglish
Pages (from-to)381-382
Number of pages2
JournalPediatric Infectious Disease Journal
Issue number4
Publication statusPublished - Apr 2010
Externally publishedYes


  • Coliform
  • Escherichia coli
  • Infection
  • Prophylaxis
  • Twins

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