Lessons in effector and NLR biology of plant-microbe systems

Aleksandra Białas; Erin K. Zess; Juan Carlos De la Concepcion; Marina Franceschetti; Helen G. Pennington; Kentaro Yoshida; Jessica L. Upson; Emilie Chanclud; Chih-Hang Wu; Thorsten Langner; Abbas Maqbool; Freya A. Varden; Lida Derevnina; Khaoula Belhaj; Koki Fujisaki; Hiromasa Saitoh; Ryohei Terauchi; Mark J. Banfield; Sophien Kamoun

doi:10.1094/MPMI-08-17-0196-FI

Lessons in effector and NLR biology of plant-microbe systems

Aleksandra Białas, Erin K. Zess, Juan Carlos De la Concepcion, Marina Franceschetti, Helen G. Pennington, Kentaro Yoshida, Jessica L. Upson, Emilie Chanclud, Chih-Hang Wu, Thorsten Langner, Abbas Maqbool, Freya A. Varden, Lida Derevnina, Khaoula Belhaj, Koki Fujisaki, Hiromasa Saitoh, Ryohei Terauchi, Mark J. Banfield, Sophien Kamoun

Research output: Contribution to journal › Review article › peer-review

77 Citations (Scopus)

Abstract

A diversity of plant-associated organisms secrete effectors-proteins and metabolites that modulate plant physiology to favor host infection and colonization. However, effectors can also activate plant immune receptors, notably nucleotide-binding domain and leucine-rich repeat region (NLR)-containing proteins, enabling plants to fight off invading organisms. This interplay between effectors, their host targets, and the matching immune receptors is shaped by intricate molecular mechanisms and exceptionally dynamic coevolution. In this article, we focus on three effectors, AVR-Pik, AVR-Pia, and AVR-Pii, from the rice blast fungus Magnaporthe oryzae (syn. Pyricularia oryzae), and their corresponding rice NLR immune receptors, Pik, Pia, and Pii, to highlight general concepts of plant-microbe interactions. We draw 12 lessons in effector and NLR biology that have emerged from studying these three little effectors and are broadly applicable to other plant-microbe systems.

Original language	English
Pages (from-to)	34-45
Number of pages	12
Journal	Molecular Plant-Microbe Interactions
Volume	31
Issue number	1
Early online date	16 Nov 2017
DOIs	https://doi.org/10.1094/MPMI-08-17-0196-FI
Publication status	Published - 18 Dec 2017

Keywords

Amino Acid Sequence
Biological Evolution
Genetic Variation
Host-Pathogen Interactions
NLR Proteins/chemistry
Plants/immunology
Selection, Genetic

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10.1094/MPMI-08-17-0196-FI

Sophien Kamoun
- S.Kamounuea.acuk
- School of Biological Sciences - Professor of Biology
- Plant Sciences - Member
Person: Research Group Member, Academic, Teaching & Research

Cite this

Białas, A., Zess, E. K., De la Concepcion, J. C., Franceschetti, M., Pennington, H. G., Yoshida, K., Upson, J. L., Chanclud, E., Wu, C-H., Langner, T., Maqbool, A., Varden, F. A., Derevnina, L., Belhaj, K., Fujisaki, K., Saitoh, H., Terauchi, R., Banfield, M. J., & Kamoun, S. (2017). Lessons in effector and NLR biology of plant-microbe systems. Molecular Plant-Microbe Interactions, 31(1), 34-45. https://doi.org/10.1094/MPMI-08-17-0196-FI

Białas, Aleksandra ; Zess, Erin K. ; De la Concepcion, Juan Carlos ; Franceschetti, Marina ; Pennington, Helen G. ; Yoshida, Kentaro ; Upson, Jessica L. ; Chanclud, Emilie ; Wu, Chih-Hang ; Langner, Thorsten ; Maqbool, Abbas ; Varden, Freya A. ; Derevnina, Lida ; Belhaj, Khaoula ; Fujisaki, Koki ; Saitoh, Hiromasa ; Terauchi, Ryohei ; Banfield, Mark J. ; Kamoun, Sophien. / Lessons in effector and NLR biology of plant-microbe systems. In: Molecular Plant-Microbe Interactions. 2017 ; Vol. 31, No. 1. pp. 34-45.

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abstract = "A diversity of plant-associated organisms secrete effectors-proteins and metabolites that modulate plant physiology to favor host infection and colonization. However, effectors can also activate plant immune receptors, notably nucleotide-binding domain and leucine-rich repeat region (NLR)-containing proteins, enabling plants to fight off invading organisms. This interplay between effectors, their host targets, and the matching immune receptors is shaped by intricate molecular mechanisms and exceptionally dynamic coevolution. In this article, we focus on three effectors, AVR-Pik, AVR-Pia, and AVR-Pii, from the rice blast fungus Magnaporthe oryzae (syn. Pyricularia oryzae), and their corresponding rice NLR immune receptors, Pik, Pia, and Pii, to highlight general concepts of plant-microbe interactions. We draw 12 lessons in effector and NLR biology that have emerged from studying these three little effectors and are broadly applicable to other plant-microbe systems.",

keywords = "Amino Acid Sequence, Biological Evolution, Genetic Variation, Host-Pathogen Interactions, NLR Proteins/chemistry, Plants/immunology, Selection, Genetic",

author = "Aleksandra Bia{\l}as and Zess, {Erin K.} and {De la Concepcion}, {Juan Carlos} and Marina Franceschetti and Pennington, {Helen G.} and Kentaro Yoshida and Upson, {Jessica L.} and Emilie Chanclud and Chih-Hang Wu and Thorsten Langner and Abbas Maqbool and Varden, {Freya A.} and Lida Derevnina and Khaoula Belhaj and Koki Fujisaki and Hiromasa Saitoh and Ryohei Terauchi and Banfield, {Mark J.} and Sophien Kamoun",

year = "2017",

month = dec,

day = "18",

doi = "10.1094/MPMI-08-17-0196-FI",

language = "English",

volume = "31",

pages = "34--45",

journal = "Molecular Plant-Microbe Interactions",

issn = "0894-0282",

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Białas, A, Zess, EK, De la Concepcion, JC, Franceschetti, M, Pennington, HG, Yoshida, K, Upson, JL, Chanclud, E, Wu, C-H, Langner, T, Maqbool, A, Varden, FA, Derevnina, L, Belhaj, K, Fujisaki, K, Saitoh, H, Terauchi, R, Banfield, MJ & Kamoun, S 2017, 'Lessons in effector and NLR biology of plant-microbe systems', Molecular Plant-Microbe Interactions, vol. 31, no. 1, pp. 34-45. https://doi.org/10.1094/MPMI-08-17-0196-FI

Lessons in effector and NLR biology of plant-microbe systems. / Białas, Aleksandra; Zess, Erin K.; De la Concepcion, Juan Carlos; Franceschetti, Marina; Pennington, Helen G.; Yoshida, Kentaro; Upson, Jessica L.; Chanclud, Emilie; Wu, Chih-Hang; Langner, Thorsten; Maqbool, Abbas; Varden, Freya A.; Derevnina, Lida; Belhaj, Khaoula; Fujisaki, Koki; Saitoh, Hiromasa; Terauchi, Ryohei; Banfield, Mark J.; Kamoun, Sophien.

In: Molecular Plant-Microbe Interactions, Vol. 31, No. 1, 18.12.2017, p. 34-45.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Lessons in effector and NLR biology of plant-microbe systems

AU - Białas, Aleksandra

AU - Zess, Erin K.

AU - De la Concepcion, Juan Carlos

AU - Franceschetti, Marina

AU - Pennington, Helen G.

AU - Yoshida, Kentaro

AU - Upson, Jessica L.

AU - Chanclud, Emilie

AU - Wu, Chih-Hang

AU - Langner, Thorsten

AU - Maqbool, Abbas

AU - Varden, Freya A.

AU - Derevnina, Lida

AU - Belhaj, Khaoula

AU - Fujisaki, Koki

AU - Saitoh, Hiromasa

AU - Terauchi, Ryohei

AU - Banfield, Mark J.

AU - Kamoun, Sophien

PY - 2017/12/18

Y1 - 2017/12/18

N2 - A diversity of plant-associated organisms secrete effectors-proteins and metabolites that modulate plant physiology to favor host infection and colonization. However, effectors can also activate plant immune receptors, notably nucleotide-binding domain and leucine-rich repeat region (NLR)-containing proteins, enabling plants to fight off invading organisms. This interplay between effectors, their host targets, and the matching immune receptors is shaped by intricate molecular mechanisms and exceptionally dynamic coevolution. In this article, we focus on three effectors, AVR-Pik, AVR-Pia, and AVR-Pii, from the rice blast fungus Magnaporthe oryzae (syn. Pyricularia oryzae), and their corresponding rice NLR immune receptors, Pik, Pia, and Pii, to highlight general concepts of plant-microbe interactions. We draw 12 lessons in effector and NLR biology that have emerged from studying these three little effectors and are broadly applicable to other plant-microbe systems.

AB - A diversity of plant-associated organisms secrete effectors-proteins and metabolites that modulate plant physiology to favor host infection and colonization. However, effectors can also activate plant immune receptors, notably nucleotide-binding domain and leucine-rich repeat region (NLR)-containing proteins, enabling plants to fight off invading organisms. This interplay between effectors, their host targets, and the matching immune receptors is shaped by intricate molecular mechanisms and exceptionally dynamic coevolution. In this article, we focus on three effectors, AVR-Pik, AVR-Pia, and AVR-Pii, from the rice blast fungus Magnaporthe oryzae (syn. Pyricularia oryzae), and their corresponding rice NLR immune receptors, Pik, Pia, and Pii, to highlight general concepts of plant-microbe interactions. We draw 12 lessons in effector and NLR biology that have emerged from studying these three little effectors and are broadly applicable to other plant-microbe systems.

KW - Amino Acid Sequence

KW - Biological Evolution

KW - Genetic Variation

KW - Host-Pathogen Interactions

KW - NLR Proteins/chemistry

KW - Plants/immunology

KW - Selection, Genetic

U2 - 10.1094/MPMI-08-17-0196-FI

DO - 10.1094/MPMI-08-17-0196-FI

M3 - Review article

C2 - 29144205

VL - 31

SP - 34

EP - 45

JO - Molecular Plant-Microbe Interactions

JF - Molecular Plant-Microbe Interactions

SN - 0894-0282

IS - 1

ER -

Lessons in effector and NLR biology of plant-microbe systems

Abstract

Keywords

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Sophien Kamoun

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