Linezolid-resistant ST36 methicillin-resistant Staphylococcus aureus associated with prolonged linezolid treatment in two paediatric cystic fibrosis patients

Robert L R Hill; Angela M Kearns; James Nash; Sarah E North; Rachel Pike; Timothy Newson; Neil Woodford; Richard Calver; David M Livermore

doi:10.1093/jac/dkp494

Linezolid-resistant ST36 methicillin-resistant Staphylococcus aureus associated with prolonged linezolid treatment in two paediatric cystic fibrosis patients

Robert L R Hill
, Angela M Kearns
, James Nash
, Sarah E North
, Rachel Pike
, Timothy Newson
, Neil Woodford
, Richard Calver
, David M Livermore

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

To describe the emergence of linezolid-resistant methicillin-resistant Staphylococcus aureus (MRSA) of sequence type (ST)36 lineage in two paediatric patients with cystic fibrosis, after long-term low-dose linezolid treatment.

Original language	English
Pages (from-to)	442-445
Number of pages	4
Journal	Journal of Antimicrobial Chemotherapy
Volume	65
Issue number	3
DOIs	https://doi.org/10.1093/jac/dkp494
Publication status	Published - Mar 2010

Keywords

Acetamides
Adolescent
Anti-Bacterial Agents
Bacterial Typing Techniques
Bacteriophage Typing
Child
Cystic Fibrosis
DNA Fingerprinting
Drug Resistance, Bacterial
Genes, rRNA
Great Britain
Humans
Male
Methicillin-Resistant Staphylococcus aureus
Microbial Sensitivity Tests
Mutation
Oxazolidinones
Polymorphism, Restriction Fragment Length
Pseudomonas aeruginosa
RNA, Bacterial
RNA, Ribosomal, 23S
Sputum
Staphylococcal Infections

Access to Document

10.1093/jac/dkp494

Cite this

Hill, R. L. R., Kearns, A. M., Nash, J., North, S. E., Pike, R., Newson, T., Woodford, N., Calver, R., & Livermore, D. M. (2010). Linezolid-resistant ST36 methicillin-resistant Staphylococcus aureus associated with prolonged linezolid treatment in two paediatric cystic fibrosis patients. Journal of Antimicrobial Chemotherapy, 65(3), 442-445. https://doi.org/10.1093/jac/dkp494

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title = "Linezolid-resistant ST36 methicillin-resistant Staphylococcus aureus associated with prolonged linezolid treatment in two paediatric cystic fibrosis patients",

abstract = "To describe the emergence of linezolid-resistant methicillin-resistant Staphylococcus aureus (MRSA) of sequence type (ST)36 lineage in two paediatric patients with cystic fibrosis, after long-term low-dose linezolid treatment.",

keywords = "Acetamides, Adolescent, Anti-Bacterial Agents, Bacterial Typing Techniques, Bacteriophage Typing, Child, Cystic Fibrosis, DNA Fingerprinting, Drug Resistance, Bacterial, Genes, rRNA, Great Britain, Humans, Male, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Mutation, Oxazolidinones, Polymorphism, Restriction Fragment Length, Pseudomonas aeruginosa, RNA, Bacterial, RNA, Ribosomal, 23S, Sputum, Staphylococcal Infections",

author = "Hill, \{Robert L R\} and Kearns, \{Angela M\} and James Nash and North, \{Sarah E\} and Rachel Pike and Timothy Newson and Neil Woodford and Richard Calver and Livermore, \{David M\}",

year = "2010",

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doi = "10.1093/jac/dkp494",

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pages = "442--445",

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}

Hill, RLR, Kearns, AM, Nash, J, North, SE, Pike, R, Newson, T, Woodford, N, Calver, R & Livermore, DM 2010, 'Linezolid-resistant ST36 methicillin-resistant Staphylococcus aureus associated with prolonged linezolid treatment in two paediatric cystic fibrosis patients', Journal of Antimicrobial Chemotherapy, vol. 65, no. 3, pp. 442-445. https://doi.org/10.1093/jac/dkp494

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AU - Hill, Robert L R

AU - Kearns, Angela M

AU - Nash, James

AU - North, Sarah E

AU - Pike, Rachel

AU - Newson, Timothy

AU - Woodford, Neil

AU - Calver, Richard

AU - Livermore, David M

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KW - Anti-Bacterial Agents

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KW - DNA Fingerprinting

KW - Drug Resistance, Bacterial

KW - Genes, rRNA

KW - Great Britain

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KW - Methicillin-Resistant Staphylococcus aureus

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KW - Mutation

KW - Oxazolidinones

KW - Polymorphism, Restriction Fragment Length

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KW - RNA, Bacterial

KW - RNA, Ribosomal, 23S

KW - Sputum

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