Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters

Bridget Maher; Judy Lloyd; Edmund G. L. Wilkins; William D. Fraser; David Back; B. Kevin Park; Munir Pirmohamed

doi:10.1177/135965350400900601

Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters

Bridget Maher, Judy Lloyd, Edmund G. L. Wilkins, William D. Fraser, David Back, B. Kevin Park, Munir Pirmohamed

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

Our results show that TNF-alpha activity in patients with LD is modulated by PIs. This was not accompanied by significant changes in body habitus or insulin resistance, although this may have been a consequence of the short follow-up in this study.

Original language	English
Pages (from-to)	879-887
Number of pages	9
Journal	Antiviral Therapy
Volume	9
Issue number	6
DOIs	https://doi.org/10.1177/135965350400900601
Publication status	Published - Dec 2004

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Cite this

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title = "Lipodystrophy in patients with HIV-1 infection: effect of stopping protease inhibitors on TNF-alpha and TNF-receptor levels, and on metabolic parameters",

abstract = "Our results show that TNF-alpha activity in patients with LD is modulated by PIs. This was not accompanied by significant changes in body habitus or insulin resistance, although this may have been a consequence of the short follow-up in this study.",

author = "Bridget Maher and Judy Lloyd and Wilkins, {Edmund G. L.} and Fraser, {William D.} and David Back and Park, {B. Kevin} and Munir Pirmohamed",

year = "2004",

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AU - Maher, Bridget

AU - Lloyd, Judy

AU - Wilkins, Edmund G. L.

AU - Fraser, William D.

AU - Back, David

AU - Park, B. Kevin

AU - Pirmohamed, Munir

PY - 2004/12

Y1 - 2004/12

N2 - Our results show that TNF-alpha activity in patients with LD is modulated by PIs. This was not accompanied by significant changes in body habitus or insulin resistance, although this may have been a consequence of the short follow-up in this study.

AB - Our results show that TNF-alpha activity in patients with LD is modulated by PIs. This was not accompanied by significant changes in body habitus or insulin resistance, although this may have been a consequence of the short follow-up in this study.

U2 - 10.1177/135965350400900601

DO - 10.1177/135965350400900601

M3 - Article

VL - 9

SP - 879

EP - 887

JO - Antiviral Therapy

JF - Antiviral Therapy

SN - 1359-6535

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ER -