Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

Neus Lozano; Wafa' T Al-Jamal; Adrian Taruttis; Nicolas Beziere; Neal C Burton; Jeroen Van den Bossche; Mariarosa Mazza; Eva Herzog; Vasilis Ntziachristos; Kostas Kostarelos

doi:10.1021/ja304499q

Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

Neus Lozano, Wafa' T Al-Jamal, Adrian Taruttis, Nicolas Beziere, Neal C Burton, Jeroen Van den Bossche, Mariarosa Mazza, Eva Herzog, Vasilis Ntziachristos, Kostas Kostarelos

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

75 Citations (Scopus)

Abstract

The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

Original language	English
Pages (from-to)	13256-13258
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	134
Issue number	32
DOIs	https://doi.org/10.1021/ja304499q
Publication status	Published - 15 Aug 2012

Keywords

Optical Imaging
Animals
Humans
Gold
Metal Nanoparticles
Liposomes

Access to Document

10.1021/ja304499q

Cite this

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title = "Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues",

abstract = "The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.",

keywords = "Optical Imaging, Animals, Humans, Gold, Metal Nanoparticles, Liposomes",

author = "Neus Lozano and Al-Jamal, {Wafa' T} and Adrian Taruttis and Nicolas Beziere and Burton, {Neal C} and {Van den Bossche}, Jeroen and Mariarosa Mazza and Eva Herzog and Vasilis Ntziachristos and Kostas Kostarelos",

year = "2012",

month = aug,

day = "15",

doi = "10.1021/ja304499q",

language = "English",

volume = "134",

pages = "13256--13258",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

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}

Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues. / Lozano, Neus; Al-Jamal, Wafa' T; Taruttis, Adrian; Beziere, Nicolas; Burton, Neal C; Van den Bossche, Jeroen; Mazza, Mariarosa; Herzog, Eva; Ntziachristos, Vasilis; Kostarelos, Kostas.

In: Journal of the American Chemical Society, Vol. 134, No. 32, 15.08.2012, p. 13256-13258.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues

AU - Lozano, Neus

AU - Al-Jamal, Wafa' T

AU - Taruttis, Adrian

AU - Beziere, Nicolas

AU - Burton, Neal C

AU - Van den Bossche, Jeroen

AU - Mazza, Mariarosa

AU - Herzog, Eva

AU - Ntziachristos, Vasilis

AU - Kostarelos, Kostas

PY - 2012/8/15

Y1 - 2012/8/15

N2 - The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

AB - The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo.

KW - Optical Imaging

KW - Animals

KW - Humans

KW - Gold

KW - Metal Nanoparticles

KW - Liposomes

U2 - 10.1021/ja304499q

DO - 10.1021/ja304499q

M3 - Article

C2 - 22852749

VL - 134

SP - 13256

EP - 13258

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

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