Intracellular analysis: Changes in the concentration of hydrogen ions can lead to cellular dysfunction. Thus, quantification of the intracellular pH in localized compartments (see A and B) is important. A pH nanosensor based on photoinduced electron transfer is described that targets acidic organelles. A combination of confocal fluorescence microscopy and spectroscopy is used for localized pH measurements within living cells.
|Number of pages||5|
|Journal||Angewandte Chemie International Edition|
|Publication status||Published - 2012|