Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study

Elizabeth Brink; Veronique Coxam; Simon Robins; Kristiina Wahala; Aedin Cassidy; Francesco Branca; PHYTOS Investigators

doi:10.1093/ajcn/87.3.761

Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study

Elizabeth Brink, Veronique Coxam, Simon Robins, Kristiina Wahala, Aedin Cassidy, Francesco Branca, PHYTOS Investigators

Research output: Contribution to journal › Article › peer-review

126 Citations (Scopus)

Abstract

Osteoporosis is a major health problem. It was hypothesized that isoflavone-containing products may be a potential alternative to hormone replacement therapy for preventing bone loss during the menopausal transition.

Original language	English
Pages (from-to)	761-770
Number of pages	10
Journal	American Journal of Clinical Nutrition
Volume	87
Issue number	3
DOIs	https://doi.org/10.1093/ajcn/87.3.761
Publication status	Published - Mar 2008

Keywords

Absorptiometry, Photon
Bone Density
Bone and Bones
Calcium
Consumer Product Safety
Double-Blind Method
Female
Food, Fortified
Humans
Isoflavones
Middle Aged
Osteoporosis, Postmenopausal
Parathyroid Hormone
Peptide Fragments
Postmenopause
Procollagen
Soybeans
Vitamin D

Access to Document

10.1093/ajcn/87.3.761Licence: Other

Cite this

Brink, E., Coxam, V., Robins, S., Wahala, K., Cassidy, A., Branca, F., & PHYTOS Investigators (2008). Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study. American Journal of Clinical Nutrition, 87(3), 761-770. https://doi.org/10.1093/ajcn/87.3.761

@article{cb286a9c70d64b4b91bf8acbb8cc6b6c,

title = "Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study",

abstract = "Osteoporosis is a major health problem. It was hypothesized that isoflavone-containing products may be a potential alternative to hormone replacement therapy for preventing bone loss during the menopausal transition.",

keywords = "Absorptiometry, Photon, Bone Density, Bone and Bones, Calcium, Consumer Product Safety, Double-Blind Method, Female, Food, Fortified, Humans, Isoflavones, Middle Aged, Osteoporosis, Postmenopausal, Parathyroid Hormone, Peptide Fragments, Postmenopause, Procollagen, Soybeans, Vitamin D",

author = "Elizabeth Brink and Veronique Coxam and Simon Robins and Kristiina Wahala and Aedin Cassidy and Francesco Branca and {PHYTOS Investigators}",

year = "2008",

month = mar,

doi = "10.1093/ajcn/87.3.761",

language = "English",

volume = "87",

pages = "761--770",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

publisher = "American Society for Nutrition",

number = "3",

}

Brink, E, Coxam, V, Robins, S, Wahala, K, Cassidy, A, Branca, F & PHYTOS Investigators 2008, 'Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study', American Journal of Clinical Nutrition, vol. 87, no. 3, pp. 761-770. https://doi.org/10.1093/ajcn/87.3.761

Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study. / Brink, Elizabeth; Coxam, Veronique; Robins, Simon et al.

In: American Journal of Clinical Nutrition, Vol. 87, No. 3, 03.2008, p. 761-770.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study

AU - Brink, Elizabeth

AU - Coxam, Veronique

AU - Robins, Simon

AU - Wahala, Kristiina

AU - Cassidy, Aedin

AU - Branca, Francesco

AU - PHYTOS Investigators

PY - 2008/3

Y1 - 2008/3

N2 - Osteoporosis is a major health problem. It was hypothesized that isoflavone-containing products may be a potential alternative to hormone replacement therapy for preventing bone loss during the menopausal transition.

AB - Osteoporosis is a major health problem. It was hypothesized that isoflavone-containing products may be a potential alternative to hormone replacement therapy for preventing bone loss during the menopausal transition.

KW - Absorptiometry, Photon

KW - Bone Density

KW - Bone and Bones

KW - Calcium

KW - Consumer Product Safety

KW - Double-Blind Method

KW - Female

KW - Food, Fortified

KW - Humans

KW - Isoflavones

KW - Middle Aged

KW - Osteoporosis, Postmenopausal

KW - Parathyroid Hormone

KW - Peptide Fragments

KW - Postmenopause

KW - Procollagen

KW - Soybeans

KW - Vitamin D

U2 - 10.1093/ajcn/87.3.761

DO - 10.1093/ajcn/87.3.761

M3 - Article

C2 - 18326616

VL - 87

SP - 761

EP - 770

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 3

ER -