Magnetic resonance imaging of the optic nerve in optic neuritis

D. H. Miller; M. R. Newton; J. C. van der Poel; E. P. du Boulay; A. M. Halliday; B. E. Kendall; G. Johnson; D. G. MacManus; I. F. Moseley; W. I. McDonald

doi:10.1212/WNL.38.2.175

Magnetic resonance imaging of the optic nerve in optic neuritis

D. H. Miller, M. R. Newton, J. C. van der Poel, E. P. du Boulay, A. M. Halliday, B. E. Kendall, G. Johnson, D. G. MacManus, I. F. Moseley, W. I. McDonald

Research output: Contribution to journal › Article › peer-review

210 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) of the optic nerves using the STIR (short inversion time inversion recovery) sequence was performed in 37 adult patients with a recent or past attack of optic neuritis. MRI revealed high-signal regions in 84% of symptomatic and 20% of asymptomatic nerves. The mean longitudinal extent of lesions was 1 cm. Slow or poor visual recovery was associated with more extensive lesions, or lesions within the optic canal. Disk swelling was usually associated with anterior lesions but also occurred with lesions in the canal. Visual evoked potentials were even more sensitive than MRI in detecting lesions and are still the investigation of choice in suspected demyelinating disease involving the optic nerve.

Original language	English
Pages (from-to)	175-179
Number of pages	5
Journal	Neurology
Volume	38
Issue number	2
DOIs	https://doi.org/10.1212/WNL.38.2.175
Publication status	Published - Feb 1988

Keywords

Adult
Female
Humans
Magnetic Resonance Imaging
Male
Optic Nerve
Pathology
Optic Neuritis
Diagnosis

Access to Document

10.1212/WNL.38.2.175

Cite this

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title = "Magnetic resonance imaging of the optic nerve in optic neuritis",

abstract = "Magnetic resonance imaging (MRI) of the optic nerves using the STIR (short inversion time inversion recovery) sequence was performed in 37 adult patients with a recent or past attack of optic neuritis. MRI revealed high-signal regions in 84% of symptomatic and 20% of asymptomatic nerves. The mean longitudinal extent of lesions was 1 cm. Slow or poor visual recovery was associated with more extensive lesions, or lesions within the optic canal. Disk swelling was usually associated with anterior lesions but also occurred with lesions in the canal. Visual evoked potentials were even more sensitive than MRI in detecting lesions and are still the investigation of choice in suspected demyelinating disease involving the optic nerve.",

keywords = "Adult, Female, Humans, Magnetic Resonance Imaging, Male, Optic Nerve, Pathology, Optic Neuritis, Diagnosis",

author = "Miller, {D. H.} and Newton, {M. R.} and {van der Poel}, {J. C.} and {du Boulay}, {E. P.} and Halliday, {A. M.} and Kendall, {B. E.} and G. Johnson and MacManus, {D. G.} and Moseley, {I. F.} and McDonald, {W. I.}",

year = "1988",

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doi = "10.1212/WNL.38.2.175",

language = "English",

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TY - JOUR

T1 - Magnetic resonance imaging of the optic nerve in optic neuritis

AU - Miller, D. H.

AU - Newton, M. R.

AU - van der Poel, J. C.

AU - du Boulay, E. P.

AU - Halliday, A. M.

AU - Kendall, B. E.

AU - Johnson, G.

AU - MacManus, D. G.

AU - Moseley, I. F.

AU - McDonald, W. I.

PY - 1988/2

Y1 - 1988/2

N2 - Magnetic resonance imaging (MRI) of the optic nerves using the STIR (short inversion time inversion recovery) sequence was performed in 37 adult patients with a recent or past attack of optic neuritis. MRI revealed high-signal regions in 84% of symptomatic and 20% of asymptomatic nerves. The mean longitudinal extent of lesions was 1 cm. Slow or poor visual recovery was associated with more extensive lesions, or lesions within the optic canal. Disk swelling was usually associated with anterior lesions but also occurred with lesions in the canal. Visual evoked potentials were even more sensitive than MRI in detecting lesions and are still the investigation of choice in suspected demyelinating disease involving the optic nerve.

AB - Magnetic resonance imaging (MRI) of the optic nerves using the STIR (short inversion time inversion recovery) sequence was performed in 37 adult patients with a recent or past attack of optic neuritis. MRI revealed high-signal regions in 84% of symptomatic and 20% of asymptomatic nerves. The mean longitudinal extent of lesions was 1 cm. Slow or poor visual recovery was associated with more extensive lesions, or lesions within the optic canal. Disk swelling was usually associated with anterior lesions but also occurred with lesions in the canal. Visual evoked potentials were even more sensitive than MRI in detecting lesions and are still the investigation of choice in suspected demyelinating disease involving the optic nerve.

KW - Adult

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Optic Nerve

KW - Pathology

KW - Optic Neuritis

KW - Diagnosis

U2 - 10.1212/WNL.38.2.175

DO - 10.1212/WNL.38.2.175

M3 - Article

VL - 38

SP - 175

EP - 179

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 2

ER -