TY - JOUR
T1 - Matrix metalloproteinase genes in Xenopus development
AU - Harrison, Michael
AU - Abu-Elmagd, Muhammad
AU - Grocott, Timothy
AU - Yates, Clara
AU - Gavrilovic, Jelena
AU - Wheeler, Grant
N1 - mid:13168 dc:ueastatus:post-print formatted dc:ueahesastaffidentifier:9411720000424 dc:uearesearchgroup:Pharmacy Practice
PY - 2004/9
Y1 - 2004/9
N2 - Matrix metalloproteinases (MMPs) are a large family of proteins in vertebrates, consisting of over 24 genes in humans, only a few of which have been identified in Xenopus. Three genes coding for MMPs in Xenopus have been identified and their expression studied during development. The membrane-bound XMMP-14 and -15 (XMT1-MMP and XMT2-MMP) both showed restricted expression patterns, the former principally localising to cranial neural crest tissues and the latter to the epidermis of the embryo. XMMP-7 codes for an MMP that lacks the hemopexin-like domain. It is expressed exclusively in macrophages or other myeloid cell types from early in development. Developmental Dynamics 231:214–220, 2004. © 2004 Wiley-Liss, Inc.
AB - Matrix metalloproteinases (MMPs) are a large family of proteins in vertebrates, consisting of over 24 genes in humans, only a few of which have been identified in Xenopus. Three genes coding for MMPs in Xenopus have been identified and their expression studied during development. The membrane-bound XMMP-14 and -15 (XMT1-MMP and XMT2-MMP) both showed restricted expression patterns, the former principally localising to cranial neural crest tissues and the latter to the epidermis of the embryo. XMMP-7 codes for an MMP that lacks the hemopexin-like domain. It is expressed exclusively in macrophages or other myeloid cell types from early in development. Developmental Dynamics 231:214–220, 2004. © 2004 Wiley-Liss, Inc.
U2 - 10.1002/dvdy.v231:1
DO - 10.1002/dvdy.v231:1
M3 - Article
VL - 231
SP - 214
EP - 220
JO - Developmental Dynamics
JF - Developmental Dynamics
SN - 1058-8388
IS - 1
ER -