Mechanical properties of Triclosan sutures

Anna Jungwirth-Weinberger, Florian Grubhofer, Mohamed A Imam, Elias Bachmann, Stephan Wirth

Research output: Contribution to journalArticlepeer-review


To avoid infections and wound healing disorders, Triclosan coated sutures have been invented. Little is known of these sutures regarding their tensile properties. Three different Triclosan coated sutures (Vicryl 1 plus, PDS 0 plus, Monocryl 3-0 plus) were tested at several time points over 42 days regarding load to failure, strain, and stiffness compared to their non-coated versions (Vicryl 1, PDS 0, Monocryl 3-0). Four different measurement points were made. Suture loops were fixed in a material testing machine over two metal bars which were moved apart creating a stress to the fiber. Unpaired, two-tailed t-test were performed for each group (untreated and treated) while level of significance was defined at a level of p < 0.05. Vicryl 1 was significantly stronger on day 14 than Vicryl 1 plus (p = 0.033). On day 28, significant changes were found in PDS 0 which was weaker compared to PDS 0 plus (p = 0.039) and Vicryl 1 which was stronger than Vicryl 1 plus (p = 0.032). We have seen that Vicryl 1 plus sutures are significantly weaker according to loading to failure after 14 and 28 days, which might cause incisional hernias. PDS 0 sutures are used to reconstruct tendons, therefore a longer durableness might be of interest as re-ruptures of tendons are problematic. Our in vitro findings support, the use of Triclosan coated PDS plus sutures and Vicryl sutures as they show a longer resistance. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1777-1782, 2018.

Original languageEnglish
Pages (from-to)1777-1782
Number of pages6
JournalJournal of Orthopaedic Research
Issue number6
Early online date2 Dec 2017
Publication statusPublished - Jun 2018
Externally publishedYes


  • Biomechanical Phenomena
  • Materials Testing
  • Polyglactin 910
  • Surgical Wound Infection/prevention & control
  • Sutures
  • Tensile Strength
  • Triclosan
  • Wound Healing

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