Medical morbidities in people following hip and knee arthroplasty: data from the Osteoarthritis Initiative

Toby Smith (Lead Author), Florence Penny, Robert Fleetcroft

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Background: Total hip (THA) and knee (TKA) arthroplasty are common orthopaedic procedures most frequently for older people. Whilst it is known that this older population frequently present with medical morbidities, no studies have previously documented the prevalence of such morbidities in people who have undergone THA or TKA. The purpose of this study was to determine the prevalence and what factors are in association with the presentation of medical morbidities in these populations.

Methods: Data from the Osteoarthritis Initiative, a population-based observational study, was assessed. In total 419 people who had undergone a THA or TKA were assessed to determine the prevalence of recorded morbidities within 12 months post-arthroplasty. All medical morbidities were then assessed using univariate and then multivariate logistic regression analysis to identify factors influencing the presentation of specific morbidities at 12 months following THA or TKA.

Results: The most common medical morbidities included: osteoporosis (16%), mild to moderate depression (8%), cancer (8%), diabetes (6%), history of stroke or TIA (6%) and asthma (5%). The medical morbidities demonstrated are similar between those who undergo THA and TKA. Only gender and ethnic origin were identified as statistically significant predictors of medical morbidities in these populations. Gender was a predictor of history of heart failure, whilst ethnic origin significantly predicted depression.

Conclusions: People who undergo THA or TKA may present with a variety of medical morbidities. Accordingly consideration should be made on how to encourage the adoption and maintenance of physical activity and healthy lifestyle choices for this population.
Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalEuropean Journal of Orthopaedic Surgery & Traumatology
Issue number1
Early online date16 Oct 2015
Publication statusPublished - Jan 2016


  • Medical multi-morbidities
  • joint replacement
  • orthopaedics
  • osteoarthritis
  • older people

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