Melanoma great debate: Targeted versus complete nodal dissection following neoadjuvant therapy for melanoma: Is it time to push forward or hold off on continued de-escalation of surgery?

The management of stage III melanoma has undergone profound change with the advent of effective systemic therapies and the growing use of neoadjuvant immunotherapy. This paper highlights the issues raised and points discussed during the Great Debates session at the 2024 SSO Conference in Atlanta, focusing on the necessity of therapeutic lymph node dissection (TLND) after index lymph node (ILN) surgery.