Mesial temporal astrocyte tau pathology in the MRC-CFAS ageing brain cohort

G Lace, P G Ince, C Brayne, G M Savva, F E Matthews, R de Silva, J E Simpson, S B Wharton

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29 Citations (Scopus)

Abstract

Glial tau pathology is seen in certain tauopathies and in ageing. We determined its frequency in ageing mesial temporal lobe and its relationship to other tau pathologies in the MRC-CFAS population-representative neuropathology cohort.
Original languageEnglish
Pages (from-to)15-24
Number of pages10
JournalDementia and Geriatric Cognitive Disorders
Volume34
Issue number1
DOIs
Publication statusPublished - 2012

Keywords

  • Aged
  • Aged, 80 and over
  • Aging
  • Apolipoproteins E
  • Astrocytes
  • Brain
  • Brain Chemistry
  • Cadaver
  • Cell Shape
  • Cohort Studies
  • Disease Progression
  • Female
  • Genotype
  • Hippocampus
  • Humans
  • Immunohistochemistry
  • Male
  • Neuroglia
  • Oligodendroglia
  • Silver Staining
  • tau Proteins

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