Molecular analysis of fluoroquinolone-resistant Salmonella Paratyphi A isolate, India

Satheesh Nair, Madhulika Unnikrishnan, Keith Turner, Subash Chandra Parija, Carol Churcher, John Wain, Belgode Narasimha Harish

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19 Citations (Scopus)

Abstract

Salmonella enterica serovar Paratyphi A is increasingly a cause of enteric fever. Sequence analysis of an Indian isolate showed a unique strain with high-level resistance to ciprofloxacin associated with double mutations in the DNA gyrase subunit gyrA (Ser83-->Phe and Asp87-->Gly) and a mutation in topoisomerase IV subunit parC (Ser80-->Arg).
Original languageEnglish
Pages (from-to)489-491
Number of pages3
JournalEmerging Infectious Diseases
Volume12
Issue number3
DOIs
Publication statusPublished - Mar 2006

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