Most dysplasia in ulcerative colitis is visible at colonoscopy

Matthew D Rutter, Brian P Saunders, Kay H Wilkinson, Michael A Kamm, Christopher B Williams, Alastair Forbes

Research output: Contribution to journalArticlepeer-review

246 Citations (Scopus)

Abstract

Patients with long-standing extensive ulcerative colitis are at increased risk for colorectal carcinoma. Because most dysplasia is believed to be macroscopically invisible, recommended surveillance protocols include multiple non-targeted colonic biopsies. It was hypothesized by us that most dysplasia is actually colonoscopically visible. This study assessed the proportion of dysplasia that has been detected macroscopically in patients who underwent colonoscopy surveillance at our center.
Original languageEnglish
Pages (from-to)334-9
Number of pages6
JournalGastrointestinal Endoscopy
Volume60
Issue number3
Publication statusPublished - Sep 2004

Keywords

  • Adenoma, Villous
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Cell Transformation, Neoplastic
  • Child
  • Cohort Studies
  • Colitis, Ulcerative
  • Colonic Polyps
  • Colonoscopy
  • Colorectal Neoplasms
  • Female
  • Humans
  • Intestinal Mucosa
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Population Surveillance
  • Precancerous Conditions
  • Retrospective Studies
  • Sensitivity and Specificity

Cite this