Most dysplasia in ulcerative colitis is visible at colonoscopy

Matthew D. Rutter; Brian P. Saunders; Kay H. Wilkinson; Michael A. Kamm; Christopher B. Williams; Alastair Forbes

doi:10.1016/S0016-5107(04)01710-9

Most dysplasia in ulcerative colitis is visible at colonoscopy

Matthew D. Rutter, Brian P. Saunders, Kay H. Wilkinson, Michael A. Kamm, Christopher B. Williams, Alastair Forbes

Research output: Contribution to journal › Article › peer-review

287 Citations (Scopus)

Abstract

Patients with long-standing extensive ulcerative colitis are at increased risk for colorectal carcinoma. Because most dysplasia is believed to be macroscopically invisible, recommended surveillance protocols include multiple non-targeted colonic biopsies. It was hypothesized by us that most dysplasia is actually colonoscopically visible. This study assessed the proportion of dysplasia that has been detected macroscopically in patients who underwent colonoscopy surveillance at our center.

Original language	English
Pages (from-to)	334-339
Number of pages	6
Journal	Gastrointestinal Endoscopy
Volume	60
Issue number	3
DOIs	https://doi.org/10.1016/S0016-5107(04)01710-9
Publication status	Published - Sep 2004

Keywords

Adenoma, Villous
Adolescent
Adult
Aged
Aged, 80 and over
Biopsy
Cell Transformation, Neoplastic
Child
Cohort Studies
Colitis, Ulcerative
Colonic Polyps
Colonoscopy
Colorectal Neoplasms
Female
Humans
Intestinal Mucosa
Longitudinal Studies
Male
Middle Aged
Population Surveillance
Precancerous Conditions
Retrospective Studies
Sensitivity and Specificity

Access to Document

10.1016/S0016-5107(04)01710-9

Cite this

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title = "Most dysplasia in ulcerative colitis is visible at colonoscopy",

abstract = "Patients with long-standing extensive ulcerative colitis are at increased risk for colorectal carcinoma. Because most dysplasia is believed to be macroscopically invisible, recommended surveillance protocols include multiple non-targeted colonic biopsies. It was hypothesized by us that most dysplasia is actually colonoscopically visible. This study assessed the proportion of dysplasia that has been detected macroscopically in patients who underwent colonoscopy surveillance at our center.",

keywords = "Adenoma, Villous, Adolescent, Adult, Aged, Aged, 80 and over, Biopsy, Cell Transformation, Neoplastic, Child, Cohort Studies, Colitis, Ulcerative, Colonic Polyps, Colonoscopy, Colorectal Neoplasms, Female, Humans, Intestinal Mucosa, Longitudinal Studies, Male, Middle Aged, Population Surveillance, Precancerous Conditions, Retrospective Studies, Sensitivity and Specificity",

author = "Rutter, {Matthew D.} and Saunders, {Brian P.} and Wilkinson, {Kay H.} and Kamm, {Michael A.} and Williams, {Christopher B.} and Alastair Forbes",

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T1 - Most dysplasia in ulcerative colitis is visible at colonoscopy

AU - Rutter, Matthew D.

AU - Saunders, Brian P.

AU - Wilkinson, Kay H.

AU - Kamm, Michael A.

AU - Williams, Christopher B.

AU - Forbes, Alastair

PY - 2004/9

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N2 - Patients with long-standing extensive ulcerative colitis are at increased risk for colorectal carcinoma. Because most dysplasia is believed to be macroscopically invisible, recommended surveillance protocols include multiple non-targeted colonic biopsies. It was hypothesized by us that most dysplasia is actually colonoscopically visible. This study assessed the proportion of dysplasia that has been detected macroscopically in patients who underwent colonoscopy surveillance at our center.

AB - Patients with long-standing extensive ulcerative colitis are at increased risk for colorectal carcinoma. Because most dysplasia is believed to be macroscopically invisible, recommended surveillance protocols include multiple non-targeted colonic biopsies. It was hypothesized by us that most dysplasia is actually colonoscopically visible. This study assessed the proportion of dysplasia that has been detected macroscopically in patients who underwent colonoscopy surveillance at our center.

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KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Biopsy

KW - Cell Transformation, Neoplastic

KW - Child

KW - Cohort Studies

KW - Colitis, Ulcerative

KW - Colonic Polyps

KW - Colonoscopy

KW - Colorectal Neoplasms

KW - Female

KW - Humans

KW - Intestinal Mucosa

KW - Longitudinal Studies

KW - Male

KW - Middle Aged

KW - Population Surveillance

KW - Precancerous Conditions

KW - Retrospective Studies

KW - Sensitivity and Specificity

U2 - 10.1016/S0016-5107(04)01710-9

DO - 10.1016/S0016-5107(04)01710-9

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JO - Gastrointestinal Endoscopy

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