MRICOM-MRI COntrast Modelling using 2D T1-T2 correlation spectra and relaxation signatures

Kevin M. Wright; Joshua Warner; Luca Venturi; Robert B. Piggott; Simon T. Donell; Brian P. Hills

doi:10.1016/j.mri.2010.02.011

MRICOM-MRI COntrast Modelling using 2D T1-T2 correlation spectra and relaxation signatures

Kevin M. Wright
, Joshua Warner
, Luca Venturi
, Robert B. Piggott
, Simon T. Donell
, Brian P. Hills

Norwich Medical School

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

Image contrast is calculated by inputting experimental 2D T(1)-T(2) relaxation spectra into the ODIN software interface. The method involves characterising a magnetic resonance imaging pulse sequence with a "relaxation signature" which describes the sensitivity of the sequence to relaxation and is independent of sample parameters. Maximising (or minimising) the overlap between the experimental 2D T(1)-T(2) relaxation spectra and the relaxation signature can then be used to maximise image contrast. The concept is illustrated using relaxation signatures for the echo planar imaging and Turbo spin-echo imaging sequences, together with in-vitro 2D T(1)-T(2) spectra for liver and cartilage.

Original language	English
Pages (from-to)	661-668
Number of pages	8
Journal	Magnetic Resonance Imaging
Volume	28
Issue number	5
Early online date	8 Apr 2010
DOIs	https://doi.org/10.1016/j.mri.2010.02.011
Publication status	Published - Jun 2010

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10.1016/j.mri.2010.02.011

Cite this

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title = "MRICOM-MRI COntrast Modelling using 2D T1-T2 correlation spectra and relaxation signatures",

abstract = "Image contrast is calculated by inputting experimental 2D T(1)-T(2) relaxation spectra into the ODIN software interface. The method involves characterising a magnetic resonance imaging pulse sequence with a {"}relaxation signature{"} which describes the sensitivity of the sequence to relaxation and is independent of sample parameters. Maximising (or minimising) the overlap between the experimental 2D T(1)-T(2) relaxation spectra and the relaxation signature can then be used to maximise image contrast. The concept is illustrated using relaxation signatures for the echo planar imaging and Turbo spin-echo imaging sequences, together with in-vitro 2D T(1)-T(2) spectra for liver and cartilage.",

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AU - Wright, Kevin M.

AU - Warner, Joshua

AU - Venturi, Luca

AU - Piggott, Robert B.

AU - Donell, Simon T.

AU - Hills, Brian P.

PY - 2010/6

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AB - Image contrast is calculated by inputting experimental 2D T(1)-T(2) relaxation spectra into the ODIN software interface. The method involves characterising a magnetic resonance imaging pulse sequence with a "relaxation signature" which describes the sensitivity of the sequence to relaxation and is independent of sample parameters. Maximising (or minimising) the overlap between the experimental 2D T(1)-T(2) relaxation spectra and the relaxation signature can then be used to maximise image contrast. The concept is illustrated using relaxation signatures for the echo planar imaging and Turbo spin-echo imaging sequences, together with in-vitro 2D T(1)-T(2) spectra for liver and cartilage.

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JF - Magnetic Resonance Imaging

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