Multiplexed detection of metabolites of narcotic drugs from a single latent fingermark

Pompi Hazarika; Sue M. Jickells; Kim Wolff; David Russell

doi:10.1021/ac1023205

Multiplexed detection of metabolites of narcotic drugs from a single latent fingermark

Pompi Hazarika, Sue M. Jickells, Kim Wolff, David Russell

Research output: Contribution to journal › Article › peer-review

104 Citations (Scopus)

Abstract

An immunoassay based technique is used for the detection of psychoactive substances in the sweat deposited within fingermarks of a narcotic drug user. Magnetic particles functionalized with antimorphine and antibenzoylecgonine antibodies were used for the detection of a metabolite of heroin (morphine) and a metabolite of cocaine (benzoylecgonine), respectively. The drug metabolites were detected individually as well as simultaneously from a single fingermark. The images of the fingermarks obtained using brightfield and fluorescence microscopy were of high evidential quality with resolution to enable identification of an individual in addition to providing information on drug usage.

Original language	English
Pages (from-to)	9150-9154
Number of pages	5
Journal	Analytical Chemistry
Volume	82
Issue number	22
DOIs	https://doi.org/10.1021/ac1023205
Publication status	Published - 2010

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10.1021/ac1023205

Cite this

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title = "Multiplexed detection of metabolites of narcotic drugs from a single latent fingermark",

abstract = "An immunoassay based technique is used for the detection of psychoactive substances in the sweat deposited within fingermarks of a narcotic drug user. Magnetic particles functionalized with antimorphine and antibenzoylecgonine antibodies were used for the detection of a metabolite of heroin (morphine) and a metabolite of cocaine (benzoylecgonine), respectively. The drug metabolites were detected individually as well as simultaneously from a single fingermark. The images of the fingermarks obtained using brightfield and fluorescence microscopy were of high evidential quality with resolution to enable identification of an individual in addition to providing information on drug usage.",

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AU - Jickells, Sue M.

AU - Wolff, Kim

AU - Russell, David

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N2 - An immunoassay based technique is used for the detection of psychoactive substances in the sweat deposited within fingermarks of a narcotic drug user. Magnetic particles functionalized with antimorphine and antibenzoylecgonine antibodies were used for the detection of a metabolite of heroin (morphine) and a metabolite of cocaine (benzoylecgonine), respectively. The drug metabolites were detected individually as well as simultaneously from a single fingermark. The images of the fingermarks obtained using brightfield and fluorescence microscopy were of high evidential quality with resolution to enable identification of an individual in addition to providing information on drug usage.

AB - An immunoassay based technique is used for the detection of psychoactive substances in the sweat deposited within fingermarks of a narcotic drug user. Magnetic particles functionalized with antimorphine and antibenzoylecgonine antibodies were used for the detection of a metabolite of heroin (morphine) and a metabolite of cocaine (benzoylecgonine), respectively. The drug metabolites were detected individually as well as simultaneously from a single fingermark. The images of the fingermarks obtained using brightfield and fluorescence microscopy were of high evidential quality with resolution to enable identification of an individual in addition to providing information on drug usage.

U2 - 10.1021/ac1023205

DO - 10.1021/ac1023205

M3 - Article

VL - 82

SP - 9150

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JO - Analytical Chemistry

JF - Analytical Chemistry

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