Murine gammadelta T cells in infections: beneficial or deleterious?

Elizabeth M Andrew, Simon R Carding

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Although the importance of gammadelta T cells in pathogen-induced immune responses is becoming increasingly apparent, it is not clear that their involvement is always of benefit to the host. Here we review evidence for the protective and damaging roles of gammadelta T cells in infection and discuss how these disparate findings might be resolved by considering the nature and properties of the pathogen, the sites of infection and conditions under which gammadelta T cell responses are initiated, and the involvement of different subsets of gammadelta T cells.
Original languageEnglish
Pages (from-to)529-536
Number of pages8
JournalMicrobes and Infection
Issue number3
Publication statusPublished - Mar 2005


  • Animals
  • Gene Expression
  • Infection
  • Inflammation
  • Mice
  • T-Lymphocyte Subsets

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