Mycobacteria in nerve trunks of long-term treated leprosy patients

J.H. Pereira; D.D. Palande; S.E. Gschmeissner

Mycobacteria in nerve trunks of long-term treated leprosy patients

J.H. Pereira, D.D. Palande, S.E. Gschmeissner

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Mycobacteria were present in 4 out of 8 mixed peripheral nerve trunks from patients (3 BT and 1 BL) treated with DDS and/or MDT for periods ranging from 21 months to 8 years. Most of the bacilli appeared to be 'whole'. Nerve destruction with areas of granulomatous infiltration appeared more active than expected. Possible reasons for a continued presence of bacilli in treated nerves and its implications in 'relapse' are discussed.

Original language	English
Pages (from-to)	134-142
Number of pages	9
Journal	Leprosy Review
Volume	62
Issue number	2
Publication status	Published - 1 Jan 1991

Cite this

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abstract = "Mycobacteria were present in 4 out of 8 mixed peripheral nerve trunks from patients (3 BT and 1 BL) treated with DDS and/or MDT for periods ranging from 21 months to 8 years. Most of the bacilli appeared to be 'whole'. Nerve destruction with areas of granulomatous infiltration appeared more active than expected. Possible reasons for a continued presence of bacilli in treated nerves and its implications in 'relapse' are discussed.",

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AB - Mycobacteria were present in 4 out of 8 mixed peripheral nerve trunks from patients (3 BT and 1 BL) treated with DDS and/or MDT for periods ranging from 21 months to 8 years. Most of the bacilli appeared to be 'whole'. Nerve destruction with areas of granulomatous infiltration appeared more active than expected. Possible reasons for a continued presence of bacilli in treated nerves and its implications in 'relapse' are discussed.

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Mycobacteria in nerve trunks of long-term treated leprosy patients

Abstract

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