NeighborNet: An agglomerative method for the construction of phylogenetic networks

David Bryant; Vincent Moulton

doi:10.1093/molbev/msh018

NeighborNet: An agglomerative method for the construction of phylogenetic networks

David Bryant, Vincent Moulton

Research output: Contribution to journal › Article › peer-review

1658 Citations (Scopus)

Abstract

We present Neighbor-Net, a distance based method for constructing phylogenetic networks that is based on the Neighbor-Joining (NJ) algorithm of Saitou and Nei. Neighbor-Net provides a snapshot of the data that can guide more detailed analysis. Unlike split decomposition, Neighbor-Net scales well and can quickly produce detailed and informative networks for several hundred taxa. We illustrate the method by reanalyzing three published data sets: a collection of 110 highly recombinant Salmonella multi-locus sequence typing sequences, the 135 “African Eve” human mitochondrial sequences published by Vigilant et al., and a collection of 12 Archeal chaperonin sequences demonstrating strong evidence for gene conversion. Neighbor-Net is available as part of the SplitsTree4 software package.

Original language	English
Pages (from-to)	255-265
Number of pages	11
Journal	Molecular Biology and Evolution
Volume	21
Issue number	2
DOIs	https://doi.org/10.1093/molbev/msh018
Publication status	Published - 2004

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10.1093/molbev/msh018

Cite this

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abstract = "We present Neighbor-Net, a distance based method for constructing phylogenetic networks that is based on the Neighbor-Joining (NJ) algorithm of Saitou and Nei. Neighbor-Net provides a snapshot of the data that can guide more detailed analysis. Unlike split decomposition, Neighbor-Net scales well and can quickly produce detailed and informative networks for several hundred taxa. We illustrate the method by reanalyzing three published data sets: a collection of 110 highly recombinant Salmonella multi-locus sequence typing sequences, the 135 “African Eve” human mitochondrial sequences published by Vigilant et al., and a collection of 12 Archeal chaperonin sequences demonstrating strong evidence for gene conversion. Neighbor-Net is available as part of the SplitsTree4 software package.",

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