Neural stem cell quiescence comes to an un-sticky end

Katherine R. Long; Charles ffrench-Constant

doi:10.1038/ncb3003

Neural stem cell quiescence comes to an un-sticky end

Katherine R. Long, Charles ffrench-Constant

Norwich Medical School

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.

Original language	English
Pages (from-to)	625-627
Number of pages	3
Journal	Nature Cell Biology
Volume	16
Issue number	7
DOIs	https://doi.org/10.1038/ncb3003
Publication status	Published - 1 Jul 2014

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10.1038/ncb3003

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abstract = "Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.",

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AB - Cell-cell interactions, a key feature of the stem cell niche, regulate many aspects of stem cell behaviour. N-cadherin-mediated anchorage of neural stem cells within the adult neural niche maintains stem cell quiescence, and its release by the metalloproteinase MT5-MMP promotes neural stem cell activation.

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Neural stem cell quiescence comes to an un-sticky end

Abstract

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