Neurotransmitter receptor homologues of Dictyostelium discoideum

Samuel J. Fountain

doi:10.1007/s12031-009-9298-0

Neurotransmitter receptor homologues of Dictyostelium discoideum

Samuel J. Fountain

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The social amoeba Dictyostelium discoideum is a genetically amenable eukaryotic cell which displays many animal cell traits and has been used to study cellular signalling for over 30 years. Recently studies have highlighted the roles that molecules associated with synaptic transmission in animals, such as glutamate, GABA and ATP play in cellular differentiation and homeostasis in this simple organism. This short review summarises the evidence for the existence of both ionotropic and metabotropic families of neurotransmitter receptors in Dictyostelium.

Original language	English
Pages (from-to)	263-266
Number of pages	4
Journal	Journal of Molecular Neuroscience
Volume	41
Issue number	2
DOIs	https://doi.org/10.1007/s12031-009-9298-0
Publication status	Published - Jun 2010

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10.1007/s12031-009-9298-0

Cite this

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abstract = "The social amoeba Dictyostelium discoideum is a genetically amenable eukaryotic cell which displays many animal cell traits and has been used to study cellular signalling for over 30 years. Recently studies have highlighted the roles that molecules associated with synaptic transmission in animals, such as glutamate, GABA and ATP play in cellular differentiation and homeostasis in this simple organism. This short review summarises the evidence for the existence of both ionotropic and metabotropic families of neurotransmitter receptors in Dictyostelium.",

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