Abstract
New biaryl iminium salt catalysts for enantioselective alkene epoxidation containing additional substitution in the heterocyclic ring are reported. The effects upon conformation and enantioselectivity of this additional substitution, and the influence of dihedral angle in these systems, has been investigated using a synthetic approach supported by density functional theory. Enantioselectivities of up to 97% ee were observed.
Original language | English |
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Pages (from-to) | 4220-4232 |
Number of pages | 13 |
Journal | Organic & Biomolecular Chemistry |
Volume | 14 |
Issue number | 18 |
Early online date | 16 Mar 2016 |
DOIs | |
Publication status | Published - 14 May 2016 |